Placental expression of adenosine A(2A) receptor and hypoxia inducible factor-1 alpha in early pregnancy, term and pre-eclamptic pregnancies: interactions with placental renin-angiotensin system

Hypoxia-inducible factors (HIFs), adenosine and tissue renin-angiotensin-system (RAS) promote angiogenesis and vascularisation. We investigated the temporal expression placental adenosine A2AR receptor and HIF-1α in early pregnancy and at delivery in normotensive (NT) and pre-eclamptic (PE) women. R...

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Bibliographic Details

Published in:	Placenta (Eastbourne) Vol. 36; no. 5; pp. 611 - 613
Main Authors:	Kurlak, L O, Williams, P J, Bulmer, J N, Broughton Pipkin, F, Mistry, H D
Format:	Journal Article
Language:	English
Published:	Netherlands 01.05.2015
Subjects:	Case-Control Studies Female Humans Hypoxia-Inducible Factor 1, alpha Subunit - metabolism Placenta - metabolism Pre-Eclampsia - metabolism Pregnancy Pregnancy Trimester, First - metabolism Receptor, Adenosine A2A - metabolism Receptors, Angiotensin - metabolism Renin-Angiotensin System Early pregnancy Placental A2AR Pre-eclampsia HIF-1α: angiotensin receptors
ISSN:	1532-3102
Online Access:	Get full text
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