Variation in PARK10 is not associated with risk and age at onset of Parkinson's disease in large clinical cohorts

A recent study in autopsy-confirmed Parkinson's disease (PD) patients and controls revived the debate about the role of PARK10 in this disorder. In an attempt to replicate these results and further understand the role of this locus in the risk and age at onset of PD, we decided to explore Neuro...

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Veröffentlicht in:	Neurobiology of aging Jg. 36; H. 10; S. 2907.e13 - 2907.e17
Hauptverfasser:	Simón-Sánchez, Javier, Heutink, Peter, Gasser, Thomas
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Elsevier Inc 01.10.2015
Schlagworte:	Adult Age of Onset Aged Cohort Studies Exome - genetics Female Genetic Association Studies Genetic Variation - genetics Genotyping Techniques Humans Internal Medicine Male Middle Aged Neurogenetics Neurology NeuroX PARK10 Parkinson Disease - epidemiology Parkinson Disease - genetics Parkinson's disease Risk Sequence Analysis, DNA - methods Whole exome sequencing Parkinson's disease Neurogenetics Whole exome sequencing NeuroX PARK10
ISSN:	0197-4580, 1558-1497
Online-Zugang:	Volltext
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