Maternal varicella antibodies in children aged less than one year: Assessment of antibody decay

To investigate maternal antibody levels to varicella in infants <12 months of age in Ontario, Canada. In this study, we included specimens from infants <12 months of age, born at [greater than or equal to]37 weeks gestational age, who had sera collected at The Hospital for Sick Children (Toron...

Full description

Saved in:

Bibliographic Details
Published in:	PloS one Vol. 18; no. 11; p. e0287765
Main Authors:	Bolotin, Shelly, Hughes, Stephanie L., Savage, Rachel D., McLachlan, Elizabeth, Severini, Alberto, Arnold, Callum, Richardson, Susan, Crowcroft, Natasha S., Deek, Shelley, Halperin, Scott A., Brown, Kevin A., Hatchette, Todd, Osman, Selma, Gubbay, Jonathan B., Science, Michelle
Format:	Journal Article
Language:	English
Published:	San Francisco Public Library of Science 10.11.2023 Public Library of Science (PLoS)
Subjects:	Age Antibodies Babies Biology and life sciences Breastfeeding & lactation Care and treatment Chicken pox Children Confidence intervals Diagnosis Diseases Emergency medical care Enzyme-linked immunosorbent assay Ethics Gestational age Glycoproteins Health aspects Immunoassay Infants Infections Information systems Medicine and Health Sciences Missing data People and Places Prophylaxis Regression analysis Research and Analysis Methods Science Policy Serology Statistical analysis Vaccines Varicella Varicella-zoster virus Viral antibodies Canada
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Abstract	To investigate maternal antibody levels to varicella in infants <12 months of age in Ontario, Canada. In this study, we included specimens from infants <12 months of age, born at [greater than or equal to]37 weeks gestational age, who had sera collected at The Hospital for Sick Children (Toronto, Canada) between 2014-2016. We tested sera using a glycoprotein-based enzyme-linked immunosorbent assay (gpELISA). We measured varicella susceptibility (antibody concentration <150mIU/mL) and mean varicella antibody concentration, and assessed the probability of susceptibility and concentration between one and 11 months of age using multivariable logistic regression and Poisson regression. We found that 32% of 196 included specimens represented infants susceptible to varicella at one month of age, increasing to nearly 80% at three months of age. At six months of age, all infants were susceptible to varicella and the predicted mean varicella antibody concentration declined to 62 mIU/mL (95% confidence interval 40, 84), well below the threshold of protection. We found that varicella maternal antibody levels wane rapidly in infants, leaving most infants susceptible by four months of age. Our findings have implications for the timing of first dose of varicella-containing vaccine, infection control measures, and infant post-exposure prophylaxis recommendations.
AbstractList	To investigate maternal antibody levels to varicella in infants <12 months of age in Ontario, Canada. In this study, we included specimens from infants <12 months of age, born at [greater than or equal to]37 weeks gestational age, who had sera collected at The Hospital for Sick Children (Toronto, Canada) between 2014-2016. We tested sera using a glycoprotein-based enzyme-linked immunosorbent assay (gpELISA). We measured varicella susceptibility (antibody concentration <150mIU/mL) and mean varicella antibody concentration, and assessed the probability of susceptibility and concentration between one and 11 months of age using multivariable logistic regression and Poisson regression. We found that 32% of 196 included specimens represented infants susceptible to varicella at one month of age, increasing to nearly 80% at three months of age. At six months of age, all infants were susceptible to varicella and the predicted mean varicella antibody concentration declined to 62 mIU/mL (95% confidence interval 40, 84), well below the threshold of protection. We found that varicella maternal antibody levels wane rapidly in infants, leaving most infants susceptible by four months of age. Our findings have implications for the timing of first dose of varicella-containing vaccine, infection control measures, and infant post-exposure prophylaxis recommendations. Objectives To investigate maternal antibody levels to varicella in infants <12 months of age in Ontario, Canada. Study design In this study, we included specimens from infants <12 months of age, born at ≥37 weeks gestational age, who had sera collected at The Hospital for Sick Children (Toronto, Canada) between 2014–2016. We tested sera using a glycoprotein-based enzyme-linked immunosorbent assay (gpELISA). We measured varicella susceptibility (antibody concentration <150mIU/mL) and mean varicella antibody concentration, and assessed the probability of susceptibility and concentration between one and 11 months of age using multivariable logistic regression and Poisson regression. Results We found that 32% of 196 included specimens represented infants susceptible to varicella at one month of age, increasing to nearly 80% at three months of age. At six months of age, all infants were susceptible to varicella and the predicted mean varicella antibody concentration declined to 62 mIU/mL (95% confidence interval 40, 84), well below the threshold of protection. Conclusions We found that varicella maternal antibody levels wane rapidly in infants, leaving most infants susceptible by four months of age. Our findings have implications for the timing of first dose of varicella-containing vaccine, infection control measures, and infant post-exposure prophylaxis recommendations. ObjectivesTo investigate maternal antibody levels to varicella in infants <12 months of age in Ontario, Canada.Study designIn this study, we included specimens from infants <12 months of age, born at ≥37 weeks gestational age, who had sera collected at The Hospital for Sick Children (Toronto, Canada) between 2014-2016. We tested sera using a glycoprotein-based enzyme-linked immunosorbent assay (gpELISA). We measured varicella susceptibility (antibody concentration <150mIU/mL) and mean varicella antibody concentration, and assessed the probability of susceptibility and concentration between one and 11 months of age using multivariable logistic regression and Poisson regression.ResultsWe found that 32% of 196 included specimens represented infants susceptible to varicella at one month of age, increasing to nearly 80% at three months of age. At six months of age, all infants were susceptible to varicella and the predicted mean varicella antibody concentration declined to 62 mIU/mL (95% confidence interval 40, 84), well below the threshold of protection.ConclusionsWe found that varicella maternal antibody levels wane rapidly in infants, leaving most infants susceptible by four months of age. Our findings have implications for the timing of first dose of varicella-containing vaccine, infection control measures, and infant post-exposure prophylaxis recommendations. To investigate maternal antibody levels to varicella in infants <12 months of age in Ontario, Canada.OBJECTIVESTo investigate maternal antibody levels to varicella in infants <12 months of age in Ontario, Canada.In this study, we included specimens from infants <12 months of age, born at ≥37 weeks gestational age, who had sera collected at The Hospital for Sick Children (Toronto, Canada) between 2014-2016. We tested sera using a glycoprotein-based enzyme-linked immunosorbent assay (gpELISA). We measured varicella susceptibility (antibody concentration <150mIU/mL) and mean varicella antibody concentration, and assessed the probability of susceptibility and concentration between one and 11 months of age using multivariable logistic regression and Poisson regression.STUDY DESIGNIn this study, we included specimens from infants <12 months of age, born at ≥37 weeks gestational age, who had sera collected at The Hospital for Sick Children (Toronto, Canada) between 2014-2016. We tested sera using a glycoprotein-based enzyme-linked immunosorbent assay (gpELISA). We measured varicella susceptibility (antibody concentration <150mIU/mL) and mean varicella antibody concentration, and assessed the probability of susceptibility and concentration between one and 11 months of age using multivariable logistic regression and Poisson regression.We found that 32% of 196 included specimens represented infants susceptible to varicella at one month of age, increasing to nearly 80% at three months of age. At six months of age, all infants were susceptible to varicella and the predicted mean varicella antibody concentration declined to 62 mIU/mL (95% confidence interval 40, 84), well below the threshold of protection.RESULTSWe found that 32% of 196 included specimens represented infants susceptible to varicella at one month of age, increasing to nearly 80% at three months of age. At six months of age, all infants were susceptible to varicella and the predicted mean varicella antibody concentration declined to 62 mIU/mL (95% confidence interval 40, 84), well below the threshold of protection.We found that varicella maternal antibody levels wane rapidly in infants, leaving most infants susceptible by four months of age. Our findings have implications for the timing of first dose of varicella-containing vaccine, infection control measures, and infant post-exposure prophylaxis recommendations.CONCLUSIONSWe found that varicella maternal antibody levels wane rapidly in infants, leaving most infants susceptible by four months of age. Our findings have implications for the timing of first dose of varicella-containing vaccine, infection control measures, and infant post-exposure prophylaxis recommendations. Objectives To investigate maternal antibody levels to varicella in infants <12 months of age in Ontario, Canada. Study design In this study, we included specimens from infants <12 months of age, born at [greater than or equal to]37 weeks gestational age, who had sera collected at The Hospital for Sick Children (Toronto, Canada) between 2014-2016. We tested sera using a glycoprotein-based enzyme-linked immunosorbent assay (gpELISA). We measured varicella susceptibility (antibody concentration <150mIU/mL) and mean varicella antibody concentration, and assessed the probability of susceptibility and concentration between one and 11 months of age using multivariable logistic regression and Poisson regression. Results We found that 32% of 196 included specimens represented infants susceptible to varicella at one month of age, increasing to nearly 80% at three months of age. At six months of age, all infants were susceptible to varicella and the predicted mean varicella antibody concentration declined to 62 mIU/mL (95% confidence interval 40, 84), well below the threshold of protection. Conclusions We found that varicella maternal antibody levels wane rapidly in infants, leaving most infants susceptible by four months of age. Our findings have implications for the timing of first dose of varicella-containing vaccine, infection control measures, and infant post-exposure prophylaxis recommendations.
Audience	Academic
Author	Severini, Alberto McLachlan, Elizabeth Richardson, Susan Gubbay, Jonathan B. Savage, Rachel D. Arnold, Callum Halperin, Scott A. Bolotin, Shelly Deek, Shelley Hughes, Stephanie L. Osman, Selma Brown, Kevin A. Hatchette, Todd Science, Michelle Crowcroft, Natasha S.
AuthorAffiliation	3 Centre for Vaccine Preventable Diseases, University of Toronto, Toronto, Ontario, Canada 8 Division of Microbiology, The Hospital for Sick Children, Toronto, Ontario, Canada 11 Department of Paediatrics, University of Toronto, Toronto, Ontario, Canada 4 Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada 12 Department of Paediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada 1 Public Health Ontario, Toronto, Ontario, Canada 10 Canadian Center for Vaccinology (CCfV), IWK Health Centre, Nova Scotia Health (NSH), and Dalhousie University, Halifax, Nova Scotia (NS), Canada Public Health England, UNITED KINGDOM 5 National Microbiology Laboratory, Public Health Agency of Canada, Ottawa, Ontario, Canada 7 Division of Infectious Diseases, The Hospital for Sick Children, Toronto, Ontario, Canada 6 Department of Medical Microbiology, University of Manitoba, Manitoba, Canada 2 Dalla Lana School of Public Health, University of Toronto, Toronto,
AuthorAffiliation_xml	– name: 6 Department of Medical Microbiology, University of Manitoba, Manitoba, Canada – name: 5 National Microbiology Laboratory, Public Health Agency of Canada, Ottawa, Ontario, Canada – name: 11 Department of Paediatrics, University of Toronto, Toronto, Ontario, Canada – name: 1 Public Health Ontario, Toronto, Ontario, Canada – name: 12 Department of Paediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada – name: Public Health England, UNITED KINGDOM – name: 9 Department of Immunization, Vaccines & Biologicals, World Helath Organization, Geneva, Switzerland – name: 2 Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada – name: 4 Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada – name: 7 Division of Infectious Diseases, The Hospital for Sick Children, Toronto, Ontario, Canada – name: 3 Centre for Vaccine Preventable Diseases, University of Toronto, Toronto, Ontario, Canada – name: 8 Division of Microbiology, The Hospital for Sick Children, Toronto, Ontario, Canada – name: 10 Canadian Center for Vaccinology (CCfV), IWK Health Centre, Nova Scotia Health (NSH), and Dalhousie University, Halifax, Nova Scotia (NS), Canada
Author_xml	– sequence: 1 givenname: Shelly orcidid: 0000-0002-9100-5928 surname: Bolotin fullname: Bolotin, Shelly – sequence: 2 givenname: Stephanie L. surname: Hughes fullname: Hughes, Stephanie L. – sequence: 3 givenname: Rachel D. surname: Savage fullname: Savage, Rachel D. – sequence: 4 givenname: Elizabeth surname: McLachlan fullname: McLachlan, Elizabeth – sequence: 5 givenname: Alberto surname: Severini fullname: Severini, Alberto – sequence: 6 givenname: Callum orcidid: 0000-0002-3245-6956 surname: Arnold fullname: Arnold, Callum – sequence: 7 givenname: Susan orcidid: 0000-0002-7751-7628 surname: Richardson fullname: Richardson, Susan – sequence: 8 givenname: Natasha S. surname: Crowcroft fullname: Crowcroft, Natasha S. – sequence: 9 givenname: Shelley surname: Deek fullname: Deek, Shelley – sequence: 10 givenname: Scott A. surname: Halperin fullname: Halperin, Scott A. – sequence: 11 givenname: Kevin A. surname: Brown fullname: Brown, Kevin A. – sequence: 12 givenname: Todd orcidid: 0000-0002-5377-2528 surname: Hatchette fullname: Hatchette, Todd – sequence: 13 givenname: Selma surname: Osman fullname: Osman, Selma – sequence: 14 givenname: Jonathan B. surname: Gubbay fullname: Gubbay, Jonathan B. – sequence: 15 givenname: Michelle surname: Science fullname: Science, Michelle
BookMark	eNqNk11r2zAUhs3oWNts_2Aww2BsF8kky5bk3oxQ9hHoKOzrVsj6SBQUKZPksvz7yYkDTSlj6MLi-Hnfo3MO57I4c96pongJwQwiAt-vfR8ct7NtDs9ARQnBzZPiAraomuIKoLN79_PiMsY1AA2iGD8rzhFpa4poe1Gwrzypwae848EIZS0vuUum89KoWBpXipWxMihX8qWSpVUxlmnFXZnTljvFw1U5jzFHN8ql0uujeldKJfjuefFUcxvVi_E7KX5--vjj-sv05vbz4np-MxWYgDSVlUCUS6xB1ShMGoowgW1FJW66TrcUgqrjdau7riKCag41VFSDTuOBVAhNilcH3631kY29iQwBnF0AbgZicSCk52u2DWbDw455btg-4MOS8ZCMsIpx2WKtieyk5rVWOXULIIBQU1LXNHduUnwYs_XdRkmRSw_cnpie_nFmxZb-jkGAUZ4TzA5vR4fgf_cqJrYxcd9-p3wfWUVpW9WQgjqjrx-gj5c3UkueKzBO-5xYDKZsTkiFAGn21OwRKh-pNkbkkWqT4yeCdyeCzCT1Jy15HyNbfP_2_-ztr1P2zT12pbhNq-htn4x38RS8OoAi-BiD0kyYxAcsv9zY3FE2rMOxJ2xYBzauQxbXD8THEf1T9hdhJQ-B
CitedBy_id	crossref_primary_10_1016_j_idnow_2025_105049 crossref_primary_10_3390_pathogens14020151
Cites_doi	10.1128/JCM.00296-19 10.1093/infdis/148.2.200 10.1097/00006454-199402000-00015 10.1093/infdis/jit143 10.1128/CVI.00397-08 10.1016/S0163-4453(17)30188-3 10.1128/CVI.13.2.214-218.2006 10.1542/peds.2019-0630 10.1016/S0140-6736(06)69561-5 10.1016/j.ijid.2020.04.082 10.1016/j.vaccine.2019.12.067 10.2807/1560-7917.ES.2019.24.42.1900233 10.1128/CVI.00131-10 10.14745/ccdr.v41i10a04 10.1542/peds.109.1.79 10.1186/s12879-021-06180-x 10.1590/S1135-57272009000500012 10.1016/j.jcv.2013.01.015 10.1007/s00431-010-1212-9 10.1016/j.vaccine.2010.06.004 10.1086/501900 10.1371/journal.pone.0129483 10.14745/ccdr.v36i00a10 10.1016/j.jcv.2011.12.010 10.1016/j.vaccine.2017.03.054 10.1016/j.vaccine.2006.01.026 10.1016/j.ijid.2017.07.009
ContentType	Journal Article
Copyright	COPYRIGHT 2023 Public Library of Science 2023 Bolotin et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. Copyright: © 2023 Bolotin et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. 2023 Bolotin et al 2023 Bolotin et al 2023 Bolotin et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Copyright_xml	– notice: COPYRIGHT 2023 Public Library of Science – notice: 2023 Bolotin et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. – notice: Copyright: © 2023 Bolotin et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. – notice: 2023 Bolotin et al 2023 Bolotin et al – notice: 2023 Bolotin et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
DBID	AAYXX CITATION IOV ISR 3V. 7QG 7QL 7QO 7RV 7SN 7SS 7T5 7TG 7TM 7U9 7X2 7X7 7XB 88E 8AO 8C1 8FD 8FE 8FG 8FH 8FI 8FJ 8FK ABJCF ABUWG AEUYN AFKRA ARAPS ATCPS AZQEC BBNVY BENPR BGLVJ BHPHI C1K CCPQU D1I DWQXO FR3 FYUFA GHDGH GNUQQ H94 HCIFZ K9. KB. KB0 KL. L6V LK8 M0K M0S M1P M7N M7P M7S NAPCQ P5Z P62 P64 PATMY PDBOC PHGZM PHGZT PIMPY PJZUB PKEHL PPXIY PQEST PQGLB PQQKQ PQUKI PTHSS PYCSY RC3 7X8 5PM DOA
DOI	10.1371/journal.pone.0287765
DatabaseName	CrossRef Gale In Context: Opposing Viewpoints Gale In Context: Science ProQuest Central (Corporate) Animal Behavior Abstracts Bacteriology Abstracts (Microbiology B) Biotechnology Research Abstracts Nursing & Allied Health Database Ecology Abstracts Entomology Abstracts (Full archive) Immunology Abstracts Meteorological & Geoastrophysical Abstracts Nucleic Acids Abstracts Virology and AIDS Abstracts Agricultural Science Collection Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) ProQuest Pharma Collection Public Health Database Technology Research Database ProQuest SciTech Collection ProQuest Technology Collection ProQuest Natural Science Collection Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) Materials Science & Engineering Collection ProQuest Central (Alumni) ProQuest One Sustainability ProQuest Central UK/Ireland Advanced Technologies & Computer Science Collection Agricultural & Environmental Science Collection ProQuest Central Essentials Biological Science Collection ProQuest Central Technology collection Natural Science Collection Environmental Sciences and Pollution Management ProQuest One Community College ProQuest Materials Science Collection ProQuest Central Korea Engineering Research Database Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student AIDS and Cancer Research Abstracts SciTech Premium Collection (via ProQuest) ProQuest Health & Medical Complete (Alumni) Materials Science Database Nursing & Allied Health Database (Alumni Edition) Meteorological & Geoastrophysical Abstracts - Academic ProQuest Engineering Collection Biological Sciences Agriculture Science Database ProQuest Health & Medical Collection Medical Database Algology Mycology and Protozoology Abstracts (Microbiology C) Biological Science Database Engineering Database Nursing & Allied Health Premium Advanced Technologies & Aerospace Database ProQuest Advanced Technologies & Aerospace Collection Biotechnology and BioEngineering Abstracts Environmental Science Database Materials Science Collection ProQuest Central Premium ProQuest One Academic Publicly Available Content Database ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Applied & Life Sciences ProQuest One Academic (retired) ProQuest One Academic UKI Edition Engineering Collection Environmental Science Collection Genetics Abstracts MEDLINE - Academic PubMed Central (Full Participant titles) DOAJ Directory of Open Access Journals
DatabaseTitle	CrossRef Agricultural Science Database Publicly Available Content Database ProQuest Central Student ProQuest Advanced Technologies & Aerospace Collection ProQuest Central Essentials Nucleic Acids Abstracts SciTech Premium Collection Environmental Sciences and Pollution Management ProQuest One Applied & Life Sciences ProQuest One Sustainability Health Research Premium Collection Meteorological & Geoastrophysical Abstracts Natural Science Collection Health & Medical Research Collection Biological Science Collection ProQuest Central (New) ProQuest Medical Library (Alumni) Engineering Collection Advanced Technologies & Aerospace Collection Engineering Database Virology and AIDS Abstracts ProQuest Biological Science Collection ProQuest One Academic Eastern Edition Agricultural Science Collection ProQuest Hospital Collection ProQuest Technology Collection Health Research Premium Collection (Alumni) Biological Science Database Ecology Abstracts ProQuest Hospital Collection (Alumni) Biotechnology and BioEngineering Abstracts Environmental Science Collection Entomology Abstracts Nursing & Allied Health Premium ProQuest Health & Medical Complete ProQuest One Academic UKI Edition Environmental Science Database ProQuest Nursing & Allied Health Source (Alumni) Engineering Research Database ProQuest One Academic Meteorological & Geoastrophysical Abstracts - Academic ProQuest One Academic (New) Technology Collection Technology Research Database ProQuest One Academic Middle East (New) Materials Science Collection ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest One Health & Nursing ProQuest Natural Science Collection ProQuest Pharma Collection ProQuest Central ProQuest Health & Medical Research Collection Genetics Abstracts ProQuest Engineering Collection Biotechnology Research Abstracts Health and Medicine Complete (Alumni Edition) ProQuest Central Korea Bacteriology Abstracts (Microbiology B) Algology Mycology and Protozoology Abstracts (Microbiology C) Agricultural & Environmental Science Collection AIDS and Cancer Research Abstracts Materials Science Database ProQuest Materials Science Collection ProQuest Public Health ProQuest Nursing & Allied Health Source ProQuest SciTech Collection Advanced Technologies & Aerospace Database ProQuest Medical Library Animal Behavior Abstracts Materials Science & Engineering Collection Immunology Abstracts ProQuest Central (Alumni) MEDLINE - Academic
DatabaseTitleList	MEDLINE - Academic Agricultural Science Database
Database_xml	– sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: PIMPY name: Publicly Available Content Database url: http://search.proquest.com/publiccontent sourceTypes: Aggregation Database
DeliveryMethod	fulltext_linktorsrc
Discipline	Sciences (General)
DocumentTitleAlternate	Maternal varicella antibody decay in children <1 year
EISSN	1932-6203
ExternalDocumentID	3069280653 oai_doaj_org_article_ad96ff7dbdfa4fe2ba901011f8744848 PMC10637651 A772307553 10_1371_journal_pone_0287765
GeographicLocations	Canada
GeographicLocations_xml	– name: Canada
GrantInformation_xml	– fundername: ;
GroupedDBID	--- 123 29O 2WC 53G 5VS 7RV 7X2 7X7 7XC 88E 8AO 8C1 8CJ 8FE 8FG 8FH 8FI 8FJ A8Z AAFWJ AAUCC AAWOE AAYXX ABDBF ABIVO ABJCF ABUWG ACCTH ACGFO ACIHN ACIWK ACPRK ACUHS ADBBV AEAQA AENEX AEUYN AFFHD AFKRA AFPKN AFRAH AHMBA ALMA_UNASSIGNED_HOLDINGS AOIJS APEBS ARAPS ATCPS BAIFH BAWUL BBNVY BBTPI BCNDV BENPR BGLVJ BHPHI BKEYQ BPHCQ BVXVI BWKFM CCPQU CITATION CS3 D1I D1J D1K DIK DU5 E3Z EAP EAS EBD EMOBN ESX EX3 F5P FPL FYUFA GROUPED_DOAJ GX1 HCIFZ HH5 HMCUK HYE IAO IEA IGS IHR IHW INH INR IOV IPY ISE ISR ITC K6- KB. KQ8 L6V LK5 LK8 M0K M1P M48 M7P M7R M7S M~E NAPCQ O5R O5S OK1 OVT P2P P62 PATMY PDBOC PHGZM PHGZT PIMPY PJZUB PPXIY PQGLB PQQKQ PROAC PSQYO PTHSS PV9 PYCSY RNS RPM RZL SV3 TR2 UKHRP WOQ WOW ~02 ~KM ALIPV BBORY 3V. 7QG 7QL 7QO 7SN 7SS 7T5 7TG 7TM 7U9 7XB 8FD 8FK AZQEC C1K DWQXO ESTFP FR3 GNUQQ H94 K9. KL. M7N P64 PKEHL PQEST PQUKI RC3 7X8 PUEGO 5PM
ID	FETCH-LOGICAL-c670t-d2c38ad6f025e67583671928d65bbf98102ba49fbb27c8fa1f1e8f0bf68367e33
IEDL.DBID	FPL
ISICitedReferencesCount	2
ISICitedReferencesURI	http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=001124284600035&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
ISSN	1932-6203
IngestDate	Wed Aug 13 01:19:03 EDT 2025 Fri Oct 03 12:52:18 EDT 2025 Tue Nov 04 02:06:13 EST 2025 Fri Sep 05 06:24:33 EDT 2025 Tue Oct 07 07:24:38 EDT 2025 Sat Nov 29 14:17:31 EST 2025 Sat Nov 29 10:56:20 EST 2025 Wed Nov 26 11:21:58 EST 2025 Wed Nov 26 11:18:52 EST 2025 Thu May 22 21:23:16 EDT 2025 Sat Nov 29 05:40:26 EST 2025 Tue Nov 18 21:30:41 EST 2025
IsDoiOpenAccess	true
IsOpenAccess	true
IsPeerReviewed	true
IsScholarly	true
Issue	11
Language	English
License	This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Creative Commons Attribution License
LinkModel	DirectLink
MergedId	FETCHMERGED-LOGICAL-c670t-d2c38ad6f025e67583671928d65bbf98102ba49fbb27c8fa1f1e8f0bf68367e33
Notes	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 Competing Interests: The authors have declared that no competing interests exist.
ORCID	0000-0002-7751-7628 0000-0002-3245-6956 0000-0002-5377-2528 0000-0002-9100-5928
OpenAccessLink	http://dx.doi.org/10.1371/journal.pone.0287765
PMID	37948389
PQID	3069280653
PQPubID	1436336
PageCount	e0287765
ParticipantIDs	plos_journals_3069280653 doaj_primary_oai_doaj_org_article_ad96ff7dbdfa4fe2ba901011f8744848 pubmedcentral_primary_oai_pubmedcentral_nih_gov_10637651 proquest_miscellaneous_2889241804 proquest_journals_3069280653 gale_infotracmisc_A772307553 gale_infotracacademiconefile_A772307553 gale_incontextgauss_ISR_A772307553 gale_incontextgauss_IOV_A772307553 gale_healthsolutions_A772307553 crossref_citationtrail_10_1371_journal_pone_0287765 crossref_primary_10_1371_journal_pone_0287765
PublicationCentury	2000
PublicationDate	2023-11-10
PublicationDateYYYYMMDD	2023-11-10
PublicationDate_xml	– month: 11 year: 2023 text: 2023-11-10 day: 10
PublicationDecade	2020
PublicationPlace	San Francisco
PublicationPlace_xml	– name: San Francisco – name: San Francisco, CA USA
PublicationTitle	PloS one
PublicationYear	2023
Publisher	Public Library of Science Public Library of Science (PLoS)
Publisher_xml	– name: Public Library of Science – name: Public Library of Science (PLoS)
References	I Peña-Rey (pone.0287765.ref029) 2009; 83 SA Plotkin (pone.0287765.ref039) 2010; 17 E McLachlan (pone.0287765.ref016) 2019; 57 pone.0287765.ref020 pone.0287765.ref021 pone.0287765.ref022 E Gowin (pone.0287765.ref005) 2017; 62 D Pinquier (pone.0287765.ref024) 2009; 16 FP Bianchi (pone.0287765.ref035) 2021; 21 pone.0287765.ref002 PA Maple (pone.0287765.ref018) 2012; 53 pone.0287765.ref003 pone.0287765.ref025 AE Wormsbecker (pone.0287765.ref009) 2015; 10 pone.0287765.ref026 U Heininger (pone.0287765.ref010) 2006; 368 pone.0287765.ref027 E Leuridan (pone.0287765.ref014) 2011; 29 pone.0287765.ref028 pone.0287765.ref008 PA Maple (pone.0287765.ref017) 2006; 13 JWJ GNANN (pone.0287765.ref040) 2012; 55 KBKPMT for Varivax (pone.0287765.ref037); 21 A Lécuyer (pone.0287765.ref011) 2010; 169 WC van der Zwet (pone.0287765.ref015) 2002; 109 S Waaijenborg (pone.0287765.ref013) 2013; 208 L Saiman (pone.0287765.ref032) 2001; 22 T Harris (pone.0287765.ref007) 2015; 41 CA Friedman (pone.0287765.ref012) 1994; 13 M Science (pone.0287765.ref019) 2019; 144 JR Duncan (pone.0287765.ref031) 2017; 35 E Tourtelot (pone.0287765.ref036) 2020; 38 AA Gershon (pone.0287765.ref001) 2017; 74 A Campbell (pone.0287765.ref006) 2010; 36 JL Bernal (pone.0287765.ref004) 2019; 24 A Trevisan (pone.0287765.ref034) 2020; 96 pone.0287765.ref038 U Heininger (pone.0287765.ref023) 2006; 24 A Behrman (pone.0287765.ref033) 2013; 57 AM Arvin (pone.0287765.ref030) 1983; 148
References_xml	– volume: 57 year: 2019 ident: pone.0287765.ref016 article-title: Calibration and Evaluation of Quantitative Antibody Titers for Varicella-Zoster Virus by Use of the BioPlex 2200 publication-title: J Clin Microbiol doi: 10.1128/JCM.00296-19 – volume: 148 start-page: 200 year: 1983 ident: pone.0287765.ref030 article-title: Immunologic Evidence of Reinfection with Varicella-Zoster Virus publication-title: J Infect Dis doi: 10.1093/infdis/148.2.200 – volume: 13 start-page: 152 year: 1994 ident: pone.0287765.ref012 article-title: Outbreak and control of varicella in a neonatal intensive care unit publication-title: Pediatr Infect Dis J doi: 10.1097/00006454-199402000-00015 – volume: 208 start-page: 10 year: 2013 ident: pone.0287765.ref013 article-title: Waning of maternal antibodies against measles, mumps, rubella, and varicella in communities with contrasting vaccination coverage publication-title: J Infect Dis doi: 10.1093/infdis/jit143 – volume: 16 start-page: 484 year: 2009 ident: pone.0287765.ref024 article-title: Prevalence of anti-varicella-zoster virus antibodies in French infants under 15 months of age publication-title: Clin Vaccine Immunol doi: 10.1128/CVI.00397-08 – ident: pone.0287765.ref008 – volume: 74 start-page: S27 issue: Suppl 1 year: 2017 ident: pone.0287765.ref001 article-title: Is chickenpox so bad, what do we know about immunity to varicella zoster virus, and what does it tell us about the future? publication-title: J Infect doi: 10.1016/S0163-4453(17)30188-3 – volume: 13 start-page: 214 year: 2006 ident: pone.0287765.ref017 article-title: Performance of a time-resolved fluorescence immunoassay for measuring varicella-zoster virus immunoglobulin G levels in adults and comparison with commercial enzyme immunoassays and Merck glycoprotein enzyme immunoassay publication-title: Clin Vaccine Immunol doi: 10.1128/CVI.13.2.214-218.2006 – volume: 144 start-page: e20190630 year: 2019 ident: pone.0287765.ref019 article-title: Measles Antibody Levels in Young Infants publication-title: Pediatrics doi: 10.1542/peds.2019-0630 – volume: 368 start-page: 1365 year: 2006 ident: pone.0287765.ref010 article-title: Varicella publication-title: The Lancet doi: 10.1016/S0140-6736(06)69561-5 – volume: 96 start-page: 228 year: 2020 ident: pone.0287765.ref034 article-title: Varicella seroepidemiology and immunization in a cohort of future healthcare workers in the pre-vaccination era publication-title: International Journal of Infectious Diseases doi: 10.1016/j.ijid.2020.04.082 – volume: 38 start-page: 1581 year: 2020 ident: pone.0287765.ref036 article-title: Women who received varicella vaccine versus natural infection have different long-term T cell immunity but similar antibody levels publication-title: Vaccine doi: 10.1016/j.vaccine.2019.12.067 – ident: pone.0287765.ref026 – ident: pone.0287765.ref003 – volume: 24 start-page: 1900233 year: 2019 ident: pone.0287765.ref004 article-title: Burden of varicella complications in secondary care, England, 2004 to 2017 publication-title: Euro Surveill doi: 10.2807/1560-7917.ES.2019.24.42.1900233 – volume: 55 year: 2012 ident: pone.0287765.ref040 article-title: Varicella-Zoster Virus: Prevention Through Vaccination publication-title: Clin Obstet Gynecol – ident: pone.0287765.ref028 – ident: pone.0287765.ref022 – volume: 17 start-page: 1055 year: 2010 ident: pone.0287765.ref039 article-title: Correlates of protection induced by vaccination publication-title: Clin Vaccine Immunol doi: 10.1128/CVI.00131-10 – volume: 41 start-page: 241 year: 2015 ident: pone.0287765.ref007 article-title: A spot of bother: Why varicella vaccine programs matter publication-title: Can Commun Dis Rep doi: 10.14745/ccdr.v41i10a04 – ident: pone.0287765.ref020 – volume: 109 start-page: 79 LP year: 2002 ident: pone.0287765.ref015 article-title: Neonatal Antibody Titers Against Varicella-Zoster Virus in Relation to Gestational Age, Birth Weight, and Maternal Titer publication-title: Pediatrics doi: 10.1542/peds.109.1.79 – volume: 21 start-page: 475 year: 2021 ident: pone.0287765.ref035 article-title: Long -term persistence of antibodies against varicella in fully immunized healthcare workers: an Italian retrospective cohort study publication-title: BMC Infect Dis doi: 10.1186/s12879-021-06180-x – volume: 83 start-page: 711 year: 2009 ident: pone.0287765.ref029 article-title: Epidemiología de la varicela en España en los períodos pre y post vacunación [Epidemiology of varicella in spain pre-and post-vaccination periods] publication-title: Rev Esp Salud Publica doi: 10.1590/S1135-57272009000500012 – volume: 57 start-page: 109 year: 2013 ident: pone.0287765.ref033 article-title: Varicella immunity in vaccinated healthcare workers publication-title: Journal of Clinical Virology doi: 10.1016/j.jcv.2013.01.015 – ident: pone.0287765.ref038 – volume: 169 start-page: 1293 year: 2010 ident: pone.0287765.ref011 article-title: Hospitalization of newborns and young infants for chickenpox in France publication-title: Eur J Pediatr doi: 10.1007/s00431-010-1212-9 – volume: 29 start-page: 2222 year: 2011 ident: pone.0287765.ref014 article-title: Kinetics of maternal antibodies against rubella and varicella in infants publication-title: Vaccine doi: 10.1016/j.vaccine.2010.06.004 – volume: 22 start-page: 279 year: 2001 ident: pone.0287765.ref032 article-title: Persistence of immunity to varicella-zoster virus after vaccination of healthcare workers publication-title: Infect Control Hosp Epidemiol doi: 10.1086/501900 – volume: 10 start-page: e0129483 year: 2015 ident: pone.0287765.ref009 article-title: Twenty years of medically-attended pediatric varicella and Herpes Zoster in Ontario, Canada: a population-based study publication-title: PLoS One doi: 10.1371/journal.pone.0129483 – volume: 36 start-page: 1 year: 2010 ident: pone.0287765.ref006 article-title: Literature Review on One-Dose and Two-Dose Varicella Vaccination: An Advisory Committee Statement (ACS) National Advisory Committee on Immunization (NACI)(†) publication-title: Can Commun Dis Rep doi: 10.14745/ccdr.v36i00a10 – volume: 53 start-page: 201 year: 2012 ident: pone.0287765.ref018 article-title: Comparison of a commercial Varicella Zoster glycoprotein IgG enzyme immunoassay with a reference time resolved fluorescence immunoassay (VZV TRFIA) for measuring VZV IgG in sera from pregnant women, sera sent for confirmatory testing and pre and post vOka publication-title: J Clin Virol doi: 10.1016/j.jcv.2011.12.010 – ident: pone.0287765.ref002 – ident: pone.0287765.ref027 – volume: 35 start-page: 2351 year: 2017 ident: pone.0287765.ref031 article-title: Varicella seroepidemiology in United States air force recruits: A retrospective cohort study comparing immunogenicity of varicella vaccination and natural infection publication-title: Vaccine doi: 10.1016/j.vaccine.2017.03.054 – volume: 24 start-page: 3258 year: 2006 ident: pone.0287765.ref023 article-title: Seroprevalence of Varicella-Zoster virus IgG antibodies in Swiss children during the first 16 months of age publication-title: Vaccine doi: 10.1016/j.vaccine.2006.01.026 – ident: pone.0287765.ref025 – ident: pone.0287765.ref021 – volume: 62 start-page: 52 year: 2017 ident: pone.0287765.ref005 article-title: Too young to be vaccinated: hospitalizations caused by varicella among children in the first year of life publication-title: International Journal of Infectious Diseases doi: 10.1016/j.ijid.2017.07.009 – volume: 21 start-page: 555 ident: pone.0287765.ref037 article-title: Vaccination with measles, mumps and rubella vaccine and varicella vaccine: safety, tolerability, immunogenicity, persistence of antibody and duration of protection against varicella in healthy children publication-title: Pediatr Infect Dis J
SSID	ssj0053866
Score	2.4464307
Snippet	Objectives To investigate maternal antibody levels to varicella in infants <12 months of age in Ontario, Canada. Study design In this study, we included... To investigate maternal antibody levels to varicella in infants <12 months of age in Ontario, Canada. In this study, we included specimens from infants <12... ObjectivesTo investigate maternal antibody levels to varicella in infants <12 months of age in Ontario, Canada.Study designIn this study, we included specimens... To investigate maternal antibody levels to varicella in infants <12 months of age in Ontario, Canada.OBJECTIVESTo investigate maternal antibody levels to... Objectives To investigate maternal antibody levels to varicella in infants <12 months of age in Ontario, Canada. Study design In this study, we included...
SourceID	plos doaj pubmedcentral proquest gale crossref
SourceType	Open Website Open Access Repository Aggregation Database Enrichment Source Index Database
StartPage	e0287765
SubjectTerms	Age Antibodies Babies Biology and life sciences Breastfeeding & lactation Care and treatment Chicken pox Children Confidence intervals Diagnosis Diseases Emergency medical care Enzyme-linked immunosorbent assay Ethics Gestational age Glycoproteins Health aspects Immunoassay Infants Infections Information systems Medicine and Health Sciences Missing data People and Places Prophylaxis Regression analysis Research and Analysis Methods Science Policy Serology Statistical analysis Vaccines Varicella Varicella-zoster virus Viral antibodies
SummonAdditionalLinks	– databaseName: DOAJ Directory of Open Access Journals dbid: DOA link: http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Li9RAEG5k8OBFXB_s6KqtCOohu3n2w9soLgq6io9lb02nHzowJMNmZmH-vVWdTpiAsB68pqtDp15dla76mpAXXprcWWYSI0WVlIL5RJY2SzJTeWMdL13A2T7_xM_OxMWF_Lp31RfWhPXwwD3jTrSVzHtua-t16V1eaywoyDKPuO2iDG2-KZdDMtX7YLBixmKjXMGzkyiX43XbuGPYUTnHzWRvIwp4_aNXnq1XbTcJOacFk3s70OkdcjuGjnTRL_mA3HDNXXIQjbOjryKC9Ot7RH3WPbYzvdIIGgSipsDBZd1izSBdNnTo4abgTixdgbuj-A-dwsrpDpT_DV2MkJ209cPsHbXO6N198vP0_Y93H5J4k0JiGE83ic1NIbRlHiIchylCwTiEdsKyqq69FBBl1LqUvq5zboTXmc-c8GntGVK6onhAZg2s4JBQBzlkoXmlUwjFpBA6T32InLhLc5dWc1IMbFUmwozjbRcrFc7OOKQbPbsUCkNFYcxJMs5a9zAb19C_RYmNtAiSHR6A6qioOuo61ZmTpyhv1XecjqauFpBxgOurqmJOngcKBMposBLnl952nfr45fwfiL5_mxC9jES-BXYYHbsf4JsQgGtCeTShBHM3k-FD1M6BK52CnE-G43GcOWjs34efjcP4UlS-xrXbTuVCQBqeibScEzHR9AmDpyPN8ndAI0d9AIlkD_-HSB6RWzlEkUmoszwis83l1j0mN83VZtldPgk2_ge-8FkM priority: 102 providerName: Directory of Open Access Journals – databaseName: Nursing & Allied Health Database dbid: 7RV link: http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1LbxMxELYgcOAClIe6pYBBSMBh233bywUFRAUSFFQg6s3y-lEiRbtpNqmUf8-M17t0JQRIXONxEnse_sYefybkmS1VYnShQlXyPMx4YcMy03EYq9wqbVhmHM_27CM7Puanp-UXv-HW-rLKPia6QK0bhXvkhwBtS3cKmL5enof4ahServonNK6SazFiY7BndjLrIzH4clH463Ipiw-9dg6WTW0OYF1lDJeUS8uRY-0fYvNkuWjaEfAcl01eWoeObv3vCG6Tmx6B0mlnMjvkiqnvkB3v4y194YmoX94l4pPsKKLphUTuIbAYCoqYVw2WHtJ5Tfur4BSikqYLiJoUt-IpDJ1uwYde0enA_Ekb2_feUm2U3N4j34_efXv7PvQPMoSqYNE61IlKudSFBaBkMNNICwYIkesirypbcgArlcxKW1UJU9zK2MaG26iyBUqaNL1PJjX8g11CDaSiqWS5jADRlZzLJLIOgDETJSbKA5L2ehHKs5XjoxkL4Y7gGGQt3XQJ1Kbw2gxIOPRadmwdf5F_gyofZJFr233QrM6Ed10hdVlYy3SlrcysgSFiSUscW3w5gGc8II_RYER3cXWIGGIKiQtE0DxPA_LUSSDfRo0FPWdy07biw-fZPwh9PRkJPfdCtoHpUNJfooAxIY_XSHJ_JAlRQ42ad9G8-1lpxS_rhJ69_f6--cnQjF-KxlebZtOKhHPI5mMeZQHhI1cZTfC4pZ7_cKTmaA-gkXjvz7_-gNxIAGaGrhBzn0zWq415SK6ri_W8XT1y7v8TSktmVw priority: 102 providerName: ProQuest
Title	Maternal varicella antibodies in children aged less than one year: Assessment of antibody decay
URI	https://www.proquest.com/docview/3069280653 https://www.proquest.com/docview/2889241804 https://pubmed.ncbi.nlm.nih.gov/PMC10637651 https://doaj.org/article/ad96ff7dbdfa4fe2ba901011f8744848 http://dx.doi.org/10.1371/journal.pone.0287765
Volume	18
WOSCitedRecordID	wos001124284600035&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
hasFullText	1
inHoldings	1
isFullTextHit
isPrint
journalDatabaseRights	– providerCode: PRVAON databaseName: DOAJ Directory of Open Access Journals customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: DOA dateStart: 20060101 isFulltext: true titleUrlDefault: https://www.doaj.org/ providerName: Directory of Open Access Journals – providerCode: PRVHPJ databaseName: ROAD: Directory of Open Access Scholarly Resources customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: M~E dateStart: 20060101 isFulltext: true titleUrlDefault: https://road.issn.org providerName: ISSN International Centre – providerCode: PRVPQU databaseName: Advanced Technologies & Aerospace Database customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: P5Z dateStart: 20061201 isFulltext: true titleUrlDefault: https://search.proquest.com/hightechjournals providerName: ProQuest – providerCode: PRVPQU databaseName: Agricultural Science Database customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: M0K dateStart: 20061201 isFulltext: true titleUrlDefault: https://search.proquest.com/agriculturejournals providerName: ProQuest – providerCode: PRVPQU databaseName: Biological Science Database customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: M7P dateStart: 20061201 isFulltext: true titleUrlDefault: http://search.proquest.com/biologicalscijournals providerName: ProQuest – providerCode: PRVPQU databaseName: Engineering Database customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: M7S dateStart: 20061201 isFulltext: true titleUrlDefault: http://search.proquest.com providerName: ProQuest – providerCode: PRVPQU databaseName: Environmental Science Database customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: PATMY dateStart: 20061201 isFulltext: true titleUrlDefault: http://search.proquest.com/environmentalscience providerName: ProQuest – providerCode: PRVPQU databaseName: Health & Medical Collection customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: 7X7 dateStart: 20061201 isFulltext: true titleUrlDefault: https://search.proquest.com/healthcomplete providerName: ProQuest – providerCode: PRVPQU databaseName: Materials Science Database customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: KB. dateStart: 20061201 isFulltext: true titleUrlDefault: http://search.proquest.com/materialsscijournals providerName: ProQuest – providerCode: PRVPQU databaseName: Nursing & Allied Health Database customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: 7RV dateStart: 20061201 isFulltext: true titleUrlDefault: https://search.proquest.com/nahs providerName: ProQuest – providerCode: PRVPQU databaseName: ProQuest Central customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: BENPR dateStart: 20061201 isFulltext: true titleUrlDefault: https://www.proquest.com/central providerName: ProQuest – providerCode: PRVPQU databaseName: Public Health Database customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: 8C1 dateStart: 20061201 isFulltext: true titleUrlDefault: https://search.proquest.com/publichealth providerName: ProQuest – providerCode: PRVPQU databaseName: Publicly Available Content Database customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: PIMPY dateStart: 20061201 isFulltext: true titleUrlDefault: http://search.proquest.com/publiccontent providerName: ProQuest – providerCode: PRVATS databaseName: Public Library of Science (PLoS) Journals Open Access customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: FPL dateStart: 20060101 isFulltext: true titleUrlDefault: http://www.plos.org/publications/ providerName: Public Library of Science
link	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV3db9MwELdYxwMvwPjQuo1iEBLwkJJP2-GtnVYxbS1RB1XhxXIcGypVSbW0k_rfc3aTQBAT8HIP8bl1znfnu_j8M0KvdCx9lRHpyJhFTsiIduIw8xxPRlpmiobK4mzPLulkwubzOPmZKP62gx9Q710l0_6qyFUfVkNKSbSH9v2AEJNsjZLL2vOC7RJSHY-7rWdr-bEo_Y0v7qyWRdkKNNtlkr-sO6MH_zvih-h-FWHiwU4lDtAdlT9CB5UNl_hNBTT99jHiY7GDgMY3wmALgUZgEPQiLUxpIV7kuD7qjcHrZHgJXhGbT-0Y_hJvwUbe40GD7IkLXffe4kxJsX2CPo_OPp1-cKoLFxxJqLt2Ml8GTGREQyCkTCYREAoRIMtIlKY6ZhCMpCKMdZr6VDItPO0ppt1UE8OpguAp6uQwgkOEFaSagaCRcCFiixkTvqttgEWV6ys36qKgngcuKzRycynGktstNgpZyU5c3EiRV1LsIqfptdqhcfyFf2imuOE1WNr2AUwXr0yTiywmWtMszbQItYJXNCUrnqfNzQAsZF303CgI3x1MbTwCH0BiAh4yioIuemk5DJ5Gbgp2volNWfLzj7N_YLqatpheV0y6AHFIUR2SgHcyOF0tzpMWJ3gF2Wo-NOpcS6XkkBrGdhfd9KxV_M_NL5pm86NG-XJVbEruMwbZusfcsItYyzRaAm635IvvFrTc6APMiHd0-8CO0T0fQkjHFlmeoM76eqOeobvyZr0or3toj05nhs6ppQwoO_V6aH94NkmmPfs1pWcdAtCLYR_o2L0wlCaWXgFNoq_QIzkfJ19-AMWtYSs
linkProvider	Public Library of Science
linkToHtml	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1LbxMxELaqgAQXoDzUQKEGgYDDtvu2Fwmh8KgaNQ0VlKriYrx-lEjRbsgmRflT_EZm9kVXQsClB67xOIlnZ74Zr8ffEPLYJso3OlaOSnjkhDy2ThJqz_FUZJU2LDQlz_bxiI3H_OQkOVwjP5q7MFhW2WBiCdQ6V_iOfAdS26Q8BQxezb452DUKT1ebFhqVWeyb1XfYshUvh2_h-T7x_d13R2_2nLqrgKNi5i4c7auASx1biPYG0-UgZpDmcB1HaWoTDhE3lWFi09RnilvpWc9w66Y2RkmDL0AB8i-Foe-iFx1GnxvkB-yI4_p6XsC8ndoatmd5ZrYhjjOGIexc-Cu7BLSxoDeb5kUn0e2WaZ6Le7vX_zeN3SDX6gybDiqXWCdrJrtJ1msMK-izmmj7-S0iDmRFgU3PJHIrgUdQMLRJmmNpJZ1ktLnqTgF1NZ1CVKB41EBB1XQFS3tBBy2zKc1tM3tFtVFydZt8upCF3iG9DP7BBqEGttqBZJF0IWNNOJe-a8sEkxnXN27UJ0FjB0LVbOzYFGQqyiNGBruySl0CrUfU1tMnTjtrVrGR_EX-NZpYK4tc4uUH-fxU1NAkpE5ia5lOtZWhNbBELNnxPIudEXjI-2QLDVRUF3NbRBQD2JhBhIiioE8elRLIJ5JhwdKpXBaFGL4__gehjx86Qk9rIZuDOpSsL4nAmpCnrCO52ZEEVFSd4Q10p0YrhfjlDTCz8ZffDz9sh_FL0fgyky8L4XOeQMLL3bBPeMc1OwrujmSTryVpO9oDPBHv7p9_fYtc2Ts6GInRcLx_j1z1IaV2yqLTTdJbzJfmPrmszhaTYv6ghB5Kvly05_4EmuXDLw
linkToPdf	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1ZbxMxELaqghAvQDnUQKEGgYCHbfa2FwmhQImIWkLEUVW8GK-PEinaDdmkKH-NX8fMXnQlBLz0gdd4nMSz3xxej78h5KFNlG90rByV8MgJeWydJNSe46nIKm1YaEqe7aNDNh7z4-NkskF-NHdhsKyy8Ymlo9a5wnfkfUhtk_IUMOjbuixisj98Mf_mYAcpPGlt2mlUEDkw6--wfSuej_bhWT_y_eHrj6_eOHWHAUfFzF062lcBlzq2EPkNps5BzCDl4TqO0tQmHKJvKsPEpqnPFLfSs57h1k1tjJIGX4aC-7_AYI-J5YST6HMTBcCPxHF9VS9gXr9Gxt48z8wexHTGMJydCYVlx4A2LmzOZ3nRSXq7JZtnYuDw6v-svWvkSp1500FlKltkw2TXyVbt2wr6pCbgfnqDiLeyosampxI5l8BSKABwmuZYckmnGW2uwFPwxprOIFpQPIKgoHa6hqU9o4OW8ZTmtpm9ptooub5JPp3LQm-RzQz-wTahBrbggWSRdCGTTTiXvmvLxJMZ1zdu1CNBgwmhapZ2bBYyE-XRI4PdWqUugUgSNZJ6xGlnzSuWkr_Iv0S4tbLIMV5-kC9ORO2yhNRJbC3TqbYytAaWiKU8nmexYwIPeY_sIlhFdWG39ZRiABs2iBxRFPTIg1ICeUYyxNyJXBWFGL07-gehD-87Qo9rIZuDOpSsL4_AmpC_rCO505EEb6k6w9toWo1WCvHLMmBmYzu_H77fDuOXIvgyk68K4XOeQCLM3bBHeMdMOwrujmTTryWZO-IBnoh3-8-_vksugcGKw9H44A657EOm7ZS1qDtkc7lYmbvkojpdTovFvdILUfLlvA33Jylcy_k
openUrl	ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Maternal+varicella+antibodies+in+children+aged+less+than+one+year%3A+Assessment+of+antibody+decay&rft.jtitle=PloS+one&rft.au=Bolotin%2C+Shelly&rft.au=Hughes%2C+Stephanie+L.&rft.au=Savage%2C+Rachel+D.&rft.au=McLachlan%2C+Elizabeth&rft.date=2023-11-10&rft.issn=1932-6203&rft.eissn=1932-6203&rft.volume=18&rft.issue=11&rft.spage=e0287765&rft_id=info:doi/10.1371%2Fjournal.pone.0287765&rft.externalDBID=n%2Fa&rft.externalDocID=10_1371_journal_pone_0287765
thumbnail_l	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1932-6203&client=summon
thumbnail_m	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1932-6203&client=summon
thumbnail_s	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1932-6203&client=summon