Effect of pomegranate extracts on brain antioxidant markers and cholinesterase activity in high fat-high fructose diet induced obesity in rat model

Background To investigate beneficial effects of Pomegranate seeds oil (PSO), leaves (PL), juice (PJ) and (PP) on brain cholinesterase activity, brain oxidative stress and lipid profile in high-fat-high fructose diet (HFD) induced-obese rat. Methods In vitro and in vivo cholinesterase activity, brain...

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Bibliographic Details
Published in:	BMC complementary and alternative medicine Vol. 17; no. 1; p. 339
Main Authors:	Amri, Zahra, Ghorbel, Asma, Turki, Mouna, Akrout, Férièle Messadi, Ayadi, Fatma, Elfeki, Abdelfateh, Hammami, Mohamed
Format:	Journal Article
Language:	English
Published:	London BioMed Central 27.06.2017 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	animal models Animals Anti-cholinesterase activity antioxidant activity Antioxidants Antioxidants - metabolism Basic research Blood blood lipids Body weight Brain Brain - drug effects Brain - enzymology Brain - metabolism Carbonyls Care and treatment Chiropractic Medicine Cholinesterase Cholinesterases Cholinesterases - metabolism complement Complementary & Alternative Medicine Complications and side effects Diet Diet, High-Fat - adverse effects Disease Models, Animal Disorders Fructose Fructose - adverse effects Fruit juices Glutathione Glutathione peroxidase Glutathione Peroxidase - metabolism Humans In vitro methods and tests In vivo methods and tests inhibitory concentration 50 Internal Medicine juices lipid composition lipids Male Malondialdehyde Malondialdehyde - metabolism Medicine Medicine & Public Health Neuroprotection Obesity Obesity - drug therapy Obesity - enzymology Obesity - metabolism oils Oils & fats oxidants Oxidative stress Oxidative Stress - drug effects Oxidizing agents Peroxidase Physiological aspects Plant Extracts - administration & dosage Pomegranate pomegranates Properties Punicaceae - chemistry Rats Rats, Wistar Research Article Rodents Seeds Stimulation Superoxide dismutase Superoxide Dismutase - metabolism Tunisia Obesity Brain Oxidative stress Pomegranate Anti-cholinesterase activity
ISSN:	1472-6882, 1472-6882
Online Access:	Get full text
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