Vagus Nerve Stimulation for the Treatment of Epilepsy

Vagus nerve stimulation (VNS) was the first neuromodulation device approved for treatment of epilepsy. In more than 20 years of study, VNS has consistently demonstrated efficacy in treating epilepsy. After 2 years, approximately 50% of patients experience at least 50% reduced seizure frequency. Adve...

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Veröffentlicht in:Neurosurgery clinics of North America Jg. 30; H. 2; S. 219
Hauptverfasser: González, Hernán F J, Yengo-Kahn, Aaron, Englot, Dario J
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States 01.04.2019
Schlagworte:
Epilepsy - therapy
Humans
Seizures - therapy
Treatment Outcome
Vagus Nerve Stimulation - methods
Vagus nerve stimulator
Epilepsy surgery
Neuromodulation
Epilepsy
Seizures
ISSN:1558-1349, 1558-1349
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Beschreibung
Zusammenfassung:Vagus nerve stimulation (VNS) was the first neuromodulation device approved for treatment of epilepsy. In more than 20 years of study, VNS has consistently demonstrated efficacy in treating epilepsy. After 2 years, approximately 50% of patients experience at least 50% reduced seizure frequency. Adverse events with VNS treatment are rare and include surgical adverse events (including infection, vocal cord paresis, and so forth) and stimulation side effects (hoarseness, voice change, and cough). Future developments in VNS, including closed-loop and noninvasive stimulation, may reduce side effects or increase efficacy of VNS.
Bibliographie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
content type line 23
ISSN:1558-1349
1558-1349
DOI:10.1016/j.nec.2018.12.005