Vagus Nerve Stimulation for the Treatment of Epilepsy

Vagus nerve stimulation (VNS) was the first neuromodulation device approved for treatment of epilepsy. In more than 20 years of study, VNS has consistently demonstrated efficacy in treating epilepsy. After 2 years, approximately 50% of patients experience at least 50% reduced seizure frequency. Adve...

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Bibliographic Details
Published in:Neurosurgery clinics of North America Vol. 30; no. 2; p. 219
Main Authors: González, Hernán F J, Yengo-Kahn, Aaron, Englot, Dario J
Format: Journal Article
Language:English
Published: United States 01.04.2019
Subjects:
Epilepsy - therapy
Humans
Seizures - therapy
Treatment Outcome
Vagus Nerve Stimulation - methods
Vagus nerve stimulator
Epilepsy surgery
Neuromodulation
Epilepsy
Seizures
ISSN:1558-1349, 1558-1349
Online Access:Get more information
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Description
Summary:Vagus nerve stimulation (VNS) was the first neuromodulation device approved for treatment of epilepsy. In more than 20 years of study, VNS has consistently demonstrated efficacy in treating epilepsy. After 2 years, approximately 50% of patients experience at least 50% reduced seizure frequency. Adverse events with VNS treatment are rare and include surgical adverse events (including infection, vocal cord paresis, and so forth) and stimulation side effects (hoarseness, voice change, and cough). Future developments in VNS, including closed-loop and noninvasive stimulation, may reduce side effects or increase efficacy of VNS.
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ISSN:1558-1349
1558-1349
DOI:10.1016/j.nec.2018.12.005