Kinetic analysis reveals the fate of a microRNA following target regulation in mammalian cells

Considerable details about microRNA (miRNA) biogenesis and regulation have been uncovered, but little is known about the fate of the miRNA subsequent to target regulation. To gain insight into this process, we carried out kinetic analysis of a miRNA's turnover following termination of its bioge...

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Vydané v:	Current biology Ročník 21; číslo 5; s. 369
Hlavní autori:	Baccarini, Alessia, Chauhan, Hemangini, Gardner, Thomas J, Jayaprakash, Anitha D, Sachidanandam, Ravi, Brown, Brian D
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England 08.03.2011
Predmet:	Base Sequence Cell Line DNA Primers - genetics Flow Cytometry Gene Expression Regulation - genetics Genetic Vectors Humans Kinetics MicroRNAs - genetics MicroRNAs - physiology Models, Genetic Molecular Sequence Data Nerve Tissue Proteins - genetics Oligonucleotides - genetics Receptors, Nerve Growth Factor - genetics RNA Stability - physiology Sequence Analysis, DNA
ISSN:	1879-0445, 1879-0445
On-line prístup:	Zistit podrobnosti o prístupe
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