Engineered cells as biosensing systems in biomedical analysis

Over the past two decades there have been great advances in biotechnology, including use of nucleic acids, proteins, and whole cells to develop a variety of molecular analytical tools for diagnostic, screening, and pharmaceutical applications. Through manipulation of bacterial plasmids and genomes,...

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Published in:	Analytical and bioanalytical chemistry Vol. 402; no. 10; pp. 3147 - 3159
Main Authors:	Raut, Nilesh, O’Connor, Gregory, Pasini, Patrizia, Daunert, Sylvia
Format:	Journal Article
Language:	English
Published:	Berlin/Heidelberg Springer-Verlag 01.04.2012 Springer
Subjects:	Analysis Analytical Chemistry Animals Antibacterial agents Assessments Bacteria Bacteria - genetics Bacterial Physiological Phenomena Biochemistry Biomedical Research Biosensing Techniques - instrumentation Biosensing Techniques - methods Characterization and Evaluation of Materials Chemistry Chemistry and Materials Science Cost analysis Detection Food Science Genes, Reporter Genetic Engineering Genomes Humans Laboratory Medicine Mathematical analysis Miniaturization Monitoring/Environmental Analysis Plasmids - genetics Plasmids - metabolism Proteins Quorum Sensing Review Screening Technology application Hydroxylated polychlorinated biphenyls Whole-cell sensing system Quorum sensing molecules Cytarabine Antibiotics Biomedical analysis Mercury
ISSN:	1618-2642, 1618-2650, 1618-2650
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Abstract	Over the past two decades there have been great advances in biotechnology, including use of nucleic acids, proteins, and whole cells to develop a variety of molecular analytical tools for diagnostic, screening, and pharmaceutical applications. Through manipulation of bacterial plasmids and genomes, bacterial whole-cell sensing systems have been engineered that can serve as novel methods for analyte detection and characterization, and as more efficient and cost-effective alternatives to traditional analytical techniques. Bacterial cell-based sensing systems are typically sensitive, specific and selective, rapid, easy to use, low-cost, and amenable to multiplexing, high-throughput, and miniaturization for incorporation into portable devices. This critical review is intended to provide an overview of available bacterial whole-cell sensing systems for assessment of a variety of clinically relevant analytes. Specifically, we examine whole-cell sensing systems for detection of bacterial quorum sensing molecules, organic and inorganic toxic compounds, and drugs, and for screening of antibacterial compounds for identification of their mechanisms of action. Methods used in the design and development of whole-cell sensing systems are also reviewed.
AbstractList	Over the past two decades there have been great advances in biotechnology, including use of nucleic acids, proteins, and whole cells to develop a variety of molecular analytical tools for diagnostic, screening, and pharmaceutical applications. Through manipulation of bacterial plasmids and genomes, bacterial whole-cell sensing systems have been engineered that can serve as novel methods for analyte detection and characterization, and as more efficient and cost-effective alternatives to traditional analytical techniques. Bacterial cell-based sensing systems are typically sensitive, specific and selective, rapid, easy to use, low-cost, and amenable to multiplexing, high-throughput, and miniaturization for incorporation into portable devices. This critical review is intended to provide an overview of available bacterial whole-cell sensing systems for assessment of a variety of clinically relevant analytes. Specifically, we examine whole-cell sensing systems for detection of bacterial quorum sensing molecules, organic and inorganic toxic compounds, and drugs, and for screening of antibacterial compounds for identification of their mechanisms of action. Methods used in the design and development of whole-cell sensing systems are also reviewed. Over the past two decades there have been great advances in biotechnology, including use of nucleic acids, proteins, and whole cells to develop a variety of molecular analytical tools for diagnostic, screening, and pharmaceutical applications. Through manipulation of bacterial plasmids and genomes, bacterial whole-cell sensing systems have been engineered that can serve as novel methods for analyte detection and characterization, and as more efficient and cost-effective alternatives to traditional analytical techniques. Bacterial cell-based sensing systems are typically sensitive, specific and selective, rapid, easy to use, low-cost, and amenable to multiplexing, high-throughput, and miniaturization for incorporation into portable devices. This critical review is intended to provide an overview of available bacterial whole-cell sensing systems for assessment of a variety of clinically relevant analytes. Specifically, we examine whole-cell sensing systems for detection of bacterial quorum sensing molecules, organic and inorganic toxic compounds, and drugs, and for screening of antibacterial compounds for identification of their mechanisms of action. Methods used in the design and development of whole-cell sensing systems are also reviewed.Over the past two decades there have been great advances in biotechnology, including use of nucleic acids, proteins, and whole cells to develop a variety of molecular analytical tools for diagnostic, screening, and pharmaceutical applications. Through manipulation of bacterial plasmids and genomes, bacterial whole-cell sensing systems have been engineered that can serve as novel methods for analyte detection and characterization, and as more efficient and cost-effective alternatives to traditional analytical techniques. Bacterial cell-based sensing systems are typically sensitive, specific and selective, rapid, easy to use, low-cost, and amenable to multiplexing, high-throughput, and miniaturization for incorporation into portable devices. This critical review is intended to provide an overview of available bacterial whole-cell sensing systems for assessment of a variety of clinically relevant analytes. Specifically, we examine whole-cell sensing systems for detection of bacterial quorum sensing molecules, organic and inorganic toxic compounds, and drugs, and for screening of antibacterial compounds for identification of their mechanisms of action. Methods used in the design and development of whole-cell sensing systems are also reviewed.
Audience	Academic
Author	Pasini, Patrizia Raut, Nilesh O’Connor, Gregory Daunert, Sylvia
Author_xml	– sequence: 1 givenname: Nilesh surname: Raut fullname: Raut, Nilesh organization: Department of Chemistry, University of Kentucky – sequence: 2 givenname: Gregory surname: O’Connor fullname: O’Connor, Gregory organization: Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami – sequence: 3 givenname: Patrizia surname: Pasini fullname: Pasini, Patrizia organization: Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami – sequence: 4 givenname: Sylvia surname: Daunert fullname: Daunert, Sylvia email: sdaunert@med.miami.edu organization: Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami
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Cites_doi	10.1128/IAI.00099-06 10.1007/s00216-006-0574-3 10.1080/10408410902733946 10.2131/jts.35.231 10.1074/jbc.M402989200 10.1177/108705719900400206 10.1177/00220345930720051601 10.1016/j.aca.2009.11.027 10.1248/jhs.46.142 10.3390/s100504558 10.1007/BF02912931 10.1248/bpb.20.107 10.1021/ac069464r 10.1373/clinchem.2010.145581 10.1146/annurev.micro.55.1.165 10.1007/BF00343125 10.1073/pnas.92.5.1490 10.1016/j.semcdb.2009.01.010 10.1111/j.1365-2958.1993.tb01737.x 10.1371/journal.pone.0019520 10.1002/elps.200800382 10.1007/s11274-009-0050-2 10.1081/AL-100002702 10.1111/j.1574-6968.1998.tb13044.x 10.1016/j.cll.2006.02.003 10.1128/AAC.49.2.749-759.2005 10.1128/AAC.48.7.2588-2594.2004 10.1007/s11356-010-0392-1 10.1080/05704920600929415 10.1128/IAI.70.4.1783-1790.2002 10.1021/ac100231a 10.1016/j.trac.2011.01.006 10.1128/AEM.00586-07 10.1021/np030096l 10.1021/ac061421n 10.1128/JB.183-1.270-279.2001 10.1016/j.bios.2011.02.022 10.1128/IAI.00550-07 10.2965/jswe.30.77 10.1128/AAC.48.4.1112-1117.2004 10.1007/s00216-011-4866-x 10.1073/pnas.1537100100 10.1038/208155a0 10.1111/j.1574-6968.2002.tb11019.x 10.1021/ac0705162 10.1046/j.1365-2672.2003.01937.x 10.1021/ac010550v 10.1016/j.femsle.2005.06.047 10.1038/35037627 10.1038/430109a 10.1128/IAI.73.6.3197-3209.2005 10.1159/000206634 10.1016/j.femsle.2005.01.055 10.1101/gr.1275704 10.1128/AAC.48.8.2838-2844.2004 10.1096/fasebj.9.7.7737458 10.1172/JCI20074 10.1128/MMBR.60.3.539-574.1996 10.1007/b13533 10.1128/IAI.67.11.5854-5862.1999
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Keywords	Hydroxylated polychlorinated biphenyls Whole-cell sensing system Quorum sensing molecules Cytarabine Antibiotics Biomedical analysis Mercury
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References	Bassler, Wright, Showalter, Silverman (CR19) 1993; 9 Rodriguez-Mozaz, de Alda, Barceló (CR1) 2006; 386 Zahir, Rizvi, Haq, Khan (CR44) 2006; 21 Erickson, Kaley (CR6) 2011; 18 Sperandio, Torres, Jarvis, Nataro, Kaper (CR20) 2003; 100 Hutter, Fischer, Jacobi, Schaab, Loferer (CR61) 2004; 48 Berglund (CR28) 1993; 72 Conroy, Hearty, Leonard, O'Kennedy (CR5) 2009; 20 Rantala, Utriainen, Kaushik, Virta, Välimaa, Karp (CR13) 2011; 400 Sanvicens, Mannelli, Salvador, Valera, Marco (CR2) 2011; 30 Kumari, Pasini, Deo, Flomenhoft, Shashidhar, Daunert (CR33) 2006; 78 Buchinger, Grill, Morosow, Ben-Yoav, Shacham-Diamand, Biran, Pedahzur, Belkin, Reifferscheid (CR12) 2010; 659 Hutter, Schaab, Albrecht, Borgmann, Brunner, Freiberg, Ziegelbauer, Rock, Ivanov, Loferer (CR62) 2004; 48 Pearson, Passador, Iglewski, Greenberg (CR34) 1995; 92 Bahl, Hansen, Licht, Sorensen (CR54) 2004; 48 Masako, Yoshio, Tomoko, Hidemitsu (CR50) 2000; 46 Roda, Cevenini, Michelini, Branchini (CR14) 2011; 26 Jaspers, Schmid, Sturme, Goslings, Kohler, Roelof van der Meer (CR38) 2001; 183 Chapman (CR64) 2004; 430 Struss, Pasini, Ensor, Raut, Daunert (CR35) 2010; 82 Kozakiewicz, Gajewska, Łyźeń, Czyź, Wȩgrzyn (CR57) 2005; 250 CR8 Stoichev, Amouroux, Martin-Doimeadios, Monperrus, Donard, Tsalev (CR46) 2006; 41 Miller, Bassler (CR16) 2001; 55 Turner, Xu, Pasini, Deo, Bachas, Daunert (CR39) 2007; 79 Alloush, Anderson, Martin, Ruddock, Angell, Hill, Mehta, Smith, Smith, Salisbury (CR56) 2010; 56 Erickson, Endersby, Kirkham, Stuber, Vollman, Rabin, Mitchell, Storey (CR30) 2002; 70 Rumbaugh, Griswold, Iglewski, Hamood (CR25) 1999; 67 Chambers, Visser, Schwab, Sokol (CR3) 2005; 244 Gu, Mitchell, Kim (CR9) 2004; 87 Kubánˇ, Pelcová, Margetínová, Kubánˇ (CR47) 2009; 30 Matsui, Yusa, Sugawara, Narita, Endo (CR49) 2007; 30 Jan, Murtaza, Ali, Rizwanul Haq (CR42) 2009; 25 Kaper, Sperandio (CR23) 2005; 73 Fischer, Brunner, Wieland, Paquette, Macko, Ziegelbauer, Freiberg (CR59) 2004; 14 CR10 Bakayan, Vaquero, Picazo, Llopis (CR37) 2011; 6 Zhang, Chung, Oldenburg (CR63) 1999; 4 Freiberg, Fischer, Brunner (CR60) 2005; 49 Newman, Cragg, Snader (CR65) 2003; 66 Walters, Sperandio (CR24) 2006; 74 Hentzer, Givskov (CR17) 2003; 112 Fantino, Barras, Denizot (CR11) 2009; 17 Yoshio, Masako, Toshiyuki, Hidemitsu (CR51) 1997; 20 Moschou, Bachas, Daunert, Deo (CR7) 2006; 78 Govan, Deretic (CR31) 1996; 60 Blake, Humphry, Scott, Hillman, Fenlon, Low (CR53) 2003; 94 Urban, Eckermann, Fast, Metzger, Gehling, Ziegelbauer, Rubsamen-Waigmann, Freiberg (CR55) 2007; 73 Freiberg, Brunner, Schiffer, Lampe, Pohlmann, Brands, Raabe, Häbich, Ziegelbauer (CR66) 2004; 279 CR26 Lorscheider, Vimy, Summers (CR40) 1995; 9 Yoo, Lee (CR4) 2010; 10 James (CR36) 2001 Ibrahim, Froberg, Wolf, Rusyniak (CR45) 2006; 26 CR22 Singh, Schaefer, Parsek, Moninger, Welsh, Greenberg (CR32) 2000; 407 Nagata, Muraoka, Kiyonoa, Pan-Hou (CR48) 2010; 35 Halbach (CR43) 1985; 57 Winson, Swift, Fish, Throup, Jørgensen, Chhabra, Bycroft, Williams, Stewart (CR27) 1998; 163 Kendall, Rasko, Sperandio (CR21) 2007; 75 Roda, Pasini, Mirasoli, Guardigli, Russo, Musiani, Baraldini (CR41) 2001; 34 Ivask, Hakkila, Virta (CR52) 2001; 73 Middleton, Rodgers, Cámara, Knox, Williams, Hardman (CR29) 2002; 207 Tomasz (CR15) 1965; 208 Czyz, Plata, Wegrzyn (CR58) 2002; 43 Antunes, Ferreira (CR18) 2009; 35 D Ibrahim (5756_CR45) 2006; 26 5756_CR9 5756_CR8 HM Alloush (5756_CR56) 2010; 56 B Middleton (5756_CR29) 2002; 207 M Erickson (5756_CR6) 2011; 18 JP Pearson (5756_CR34) 1995; 92 A Ivask (5756_CR52) 2001; 73 A Kumari (5756_CR33) 2006; 78 E-H Yoo (5756_CR4) 2010; 10 K Turner (5756_CR39) 2007; 79 A Rantala (5756_CR13) 2011; 400 MO James (5756_CR36) 2001 J Kozakiewicz (5756_CR57) 2005; 250 F Zahir (5756_CR44) 2006; 21 M Walters (5756_CR24) 2006; 74 A Roda (5756_CR14) 2011; 26 A Berglund (5756_CR28) 1993; 72 PJ Conroy (5756_CR5) 2009; 20 DJ Newman (5756_CR65) 2003; 66 A Bakayan (5756_CR37) 2011; 6 K Matsui (5756_CR49) 2007; 30 J-H Zhang (5756_CR63) 1999; 4 C Freiberg (5756_CR60) 2005; 49 T Chapman (5756_CR64) 2004; 430 J-R Fantino (5756_CR11) 2009; 17 T Stoichev (5756_CR46) 2006; 41 A Czyz (5756_CR58) 2002; 43 BL Bassler (5756_CR19) 1993; 9 S Halbach (5756_CR43) 1985; 57 F Lorscheider (5756_CR40) 1995; 9 A Roda (5756_CR41) 2001; 34 U Yoshio (5756_CR51) 1997; 20 DL Erickson (5756_CR30) 2002; 70 A Struss (5756_CR35) 2010; 82 B Hutter (5756_CR61) 2004; 48 MB Miller (5756_CR16) 2001; 55 P Kubánˇ (5756_CR47) 2009; 30 A Tomasz (5756_CR15) 1965; 208 MCM Jaspers (5756_CR38) 2001; 183 A Urban (5756_CR55) 2007; 73 C Freiberg (5756_CR66) 2004; 279 HP Fischer (5756_CR59) 2004; 14 N Sanvicens (5756_CR2) 2011; 30 CE Chambers (5756_CR3) 2005; 244 LCM Antunes (5756_CR18) 2009; 35 KP Rumbaugh (5756_CR25) 1999; 67 5756_CR26 5756_CR22 V Sperandio (5756_CR20) 2003; 100 A Jan (5756_CR42) 2009; 25 MK Winson (5756_CR27) 1998; 163 MI Bahl (5756_CR54) 2004; 48 J Govan (5756_CR31) 1996; 60 MM Kendall (5756_CR21) 2007; 75 EA Moschou (5756_CR7) 2006; 78 S Buchinger (5756_CR12) 2010; 659 M Hentzer (5756_CR17) 2003; 112 DP Blake (5756_CR53) 2003; 94 K Masako (5756_CR50) 2000; 46 JB Kaper (5756_CR23) 2005; 73 PK Singh (5756_CR32) 2000; 407 B Hutter (5756_CR62) 2004; 48 T Nagata (5756_CR48) 2010; 35 S Rodriguez-Mozaz (5756_CR1) 2006; 386 5756_CR10
References_xml	– ident: CR22 – volume: 60 start-page: 539 issue: 3 year: 1996 end-page: 574 ident: CR31 article-title: Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Burkholderia cepacia publication-title: Microbiol Rev – volume: 74 start-page: 5445 issue: 10 year: 2006 end-page: 5455 ident: CR24 article-title: Autoinducer 3 and epinephrine signaling in the kinetics of locus of enterocyte effacement gene expression in enterohemorrhagic Escherichia coli publication-title: Infect Immun doi: 10.1128/IAI.00099-06 – volume: 386 start-page: 1025 issue: 4 year: 2006 end-page: 1041 ident: CR1 article-title: Biosensors as useful tools for environmental analysis and monitoring publication-title: Anal Bioanal Chem doi: 10.1007/s00216-006-0574-3 – volume: 35 start-page: 69 issue: 2 year: 2009 end-page: 80 ident: CR18 article-title: Intercellular communication in bacteria publication-title: Crit Rev Microbiol doi: 10.1080/10408410902733946 – volume: 35 start-page: 231 issue: 2 year: 2010 end-page: 234 ident: CR48 article-title: Development of a luminescence-based biosensor for detection of methylmercury publication-title: J Toxicol Sci doi: 10.2131/jts.35.231 – volume: 279 start-page: 26066 issue: 25 year: 2004 end-page: 26073 ident: CR66 article-title: Identification and characterization of the first class of potent bacterial Acetyl-CoA carboxylase inhibitors with antibacterial activity publication-title: J Biol Chem doi: 10.1074/jbc.M402989200 – volume: 4 start-page: 67 issue: 2 year: 1999 end-page: 73 ident: CR63 article-title: A simple statistical parameter for use in evaluation and validation of high throughput screening assays publication-title: J Biomol Screen doi: 10.1177/108705719900400206 – volume: 72 start-page: 939 issue: 5 year: 1993 end-page: 946 ident: CR28 article-title: An in vitro and in vivo study of the release of mercury vapor from different types of amalgam alloys publication-title: J Dent Res doi: 10.1177/00220345930720051601 – volume: 659 start-page: 122 issue: 1–2 year: 2010 end-page: 128 ident: CR12 article-title: Evaluation of chrono-amperometric signal detection for the analysis of genotoxicity by a whole cell biosensor publication-title: Anal Chim Acta doi: 10.1016/j.aca.2009.11.027 – ident: CR8 – volume: 46 start-page: 142 issue: 2 year: 2000 end-page: 145 ident: CR50 article-title: Involvement of merB in the expression of the pMR26 mer operon induced by organomercurials publication-title: J Heal Sci doi: 10.1248/jhs.46.142 – volume: 10 start-page: 4558 issue: 5 year: 2010 end-page: 4576 ident: CR4 article-title: Glucose biosensors: an overview of use in clinical practice publication-title: Sens doi: 10.3390/s100504558 – volume: 21 start-page: 149 issue: 2 year: 2006 end-page: 152 ident: CR44 article-title: Effect of methyl mercury induced free radical stress on nucleic acids and protein: Implications on cognitive and motor functions publication-title: Indian J Clin Biochem doi: 10.1007/BF02912931 – volume: 20 start-page: 107 issue: 1 year: 1997 end-page: 109 ident: CR51 article-title: Phenylmercury transport mediated by merT-merP genes of Pseudomonas K-62 plasmid pMR26 publication-title: Biol Pharm Bull doi: 10.1248/bpb.20.107 – volume: 78 start-page: 6692 issue: 19 year: 2006 end-page: 6700 ident: CR7 article-title: Hinge-motion binding proteins: unraveling their analytical potential publication-title: Anal Chem doi: 10.1021/ac069464r – volume: 56 start-page: 1862 issue: 12 year: 2010 end-page: 1870 ident: CR56 article-title: A bioluminescent microbial biosensor for in vitro pretreatment assessment of Cytarabine efficacy in leukemia publication-title: Clin Chem doi: 10.1373/clinchem.2010.145581 – volume: 55 start-page: 165 issue: 1 year: 2001 end-page: 199 ident: CR16 article-title: Quorum sensing in bacteria publication-title: Annu Rev Microbiol doi: 10.1146/annurev.micro.55.1.165 – start-page: 35 year: 2001 end-page: 46 ident: CR36 publication-title: PCBs, recent advances in environmental toxicology and health effects – volume: 57 start-page: 139 issue: 2 year: 1985 end-page: 141 ident: CR43 article-title: The octanol/water distribution of mercury compounds publication-title: Arch Toxicol doi: 10.1007/BF00343125 – volume: 43 start-page: 377 issue: 3 year: 2002 end-page: 389 ident: CR58 article-title: Induction of light emission by luminescent bacteria treated with UV light and chemical mutagens publication-title: J Appl Genet – volume: 92 start-page: 1490 issue: 5 year: 1995 end-page: 1494 ident: CR34 article-title: A second N-acyl homoserine lactone signal produced by Pseudomonas aeruginosa publication-title: Proc Natl Acad Sci doi: 10.1073/pnas.92.5.1490 – volume: 20 start-page: 10 issue: 1 year: 2009 end-page: 26 ident: CR5 article-title: Antibody production, design and use for biosensor-based applications publication-title: Semin Cell Dev Biol doi: 10.1016/j.semcdb.2009.01.010 – volume: 9 start-page: 773 issue: 4 year: 1993 end-page: 786 ident: CR19 article-title: Intercellular signalling in Vibrio harveyi: sequence and function of genes regulating expression of luminescence publication-title: Mol Microbiol doi: 10.1111/j.1365-2958.1993.tb01737.x – volume: 67 start-page: 5854 issue: 11 year: 1999 end-page: 5862 ident: CR25 article-title: Contribution of quorum sensing to the virulence of Pseudomonas aeruginosa in burn wound infections publication-title: Infect Immun – volume: 9 start-page: 504 issue: 7 year: 1995 end-page: 508 ident: CR40 article-title: Mercury exposure from "silver" tooth fillings: emerging evidence questions a traditional dental paradigm publication-title: FASEB J – volume: 6 start-page: e19520 issue: 5 year: 2011 ident: CR37 article-title: Red fluorescent protein-aequorin fusions as improved bioluminescent Ca2+ reporters in single cells and mice publication-title: PLoS One doi: 10.1371/journal.pone.0019520 – volume: 30 start-page: 92 issue: 1 year: 2009 end-page: 99 ident: CR47 article-title: Mercury speciation by CE: An update publication-title: Electrophoresis doi: 10.1002/elps.200800382 – volume: 25 start-page: 1529 issue: 9 year: 2009 end-page: 1537 ident: CR42 article-title: Mercury pollution: an emerging problem and potential bacterial remediation strategies publication-title: World J Microbiol Biotechnol doi: 10.1007/s11274-009-0050-2 – volume: 34 start-page: 29 issue: 1 year: 2001 ident: CR41 article-title: Sensitive determination of urinary Mercury(II) by a bioluminescent transgenic bacteria-based biosensor publication-title: Anal Lett doi: 10.1081/AL-100002702 – ident: CR26 – volume: 112 start-page: 1300 issue: 9 year: 2003 end-page: 1307 ident: CR17 article-title: Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections publication-title: J Clin Invest – volume: 163 start-page: 185 issue: 2 year: 1998 end-page: 192 ident: CR27 article-title: Construction and analysis of luxCDABE-based plasmid sensors for investigating N-acyl homoserine lactone-mediated quorum sensing publication-title: FEMS Microbiol Lett doi: 10.1111/j.1574-6968.1998.tb13044.x – volume: 26 start-page: 67 issue: 1 year: 2006 end-page: 97 ident: CR45 article-title: Heavy metal poisoning: clinical presentations and pathophysiology publication-title: Clin Lab Med doi: 10.1016/j.cll.2006.02.003 – volume: 49 start-page: 749 issue: 2 year: 2005 end-page: 759 ident: CR60 article-title: Discovering the mechanism of action of novel antibacterial agents through transcriptional profiling of conditional mutants publication-title: Antimicrob Agents Chemother doi: 10.1128/AAC.49.2.749-759.2005 – volume: 48 start-page: 2588 issue: 7 year: 2004 end-page: 2594 ident: CR61 article-title: Panel of Bacillus subtilis reporter strains indicative of various modes of action publication-title: Antimicrob Agents Chemother doi: 10.1128/AAC.48.7.2588-2594.2004 – volume: 18 start-page: 135 issue: 2 year: 2011 end-page: 151 ident: CR6 article-title: Applications of polychlorinated biphenyls publication-title: Environ Sci Pollut Res doi: 10.1007/s11356-010-0392-1 – volume: 41 start-page: 591 issue: 6 year: 2006 end-page: 619 ident: CR46 article-title: Speciation analysis of mercury in aquatic environment publication-title: Appl Spectrosc Rev doi: 10.1080/05704920600929415 – volume: 87 start-page: 269 year: 2004 end-page: 305 ident: CR9 article-title: Whole-cell-based biosensors for environmental biomonitoring and application publication-title: Adv Biochem Engin/Biotechnol – volume: 70 start-page: 1783 issue: 4 year: 2002 end-page: 1790 ident: CR30 article-title: Pseudomonas aeruginosa quorum-sensing systems may control virulence factor expression in the lungs of patients with cystic fibrosis publication-title: Infect Immun doi: 10.1128/IAI.70.4.1783-1790.2002 – volume: 82 start-page: 4457 issue: 11 year: 2010 end-page: 4463 ident: CR35 article-title: Paper strip whole cell biosensors: A portable test for the semiquantitative detection of bacterial quorum signaling molecules publication-title: Anal Chem doi: 10.1021/ac100231a – volume: 30 start-page: 541 issue: 3 year: 2011 end-page: 553 ident: CR2 article-title: Biosensors for pharmaceuticals based on novel technology publication-title: Trends Anal Chem doi: 10.1016/j.trac.2011.01.006 – volume: 73 start-page: 6436 issue: 20 year: 2007 end-page: 6443 ident: CR55 article-title: Novel whole-cell antibiotic biosensors for compound discovery publication-title: Appl Environ Microbiol doi: 10.1128/AEM.00586-07 – volume: 66 start-page: 1022 issue: 7 year: 2003 end-page: 1037 ident: CR65 article-title: Natural products as sources of new drugs over the period 1981−2002 publication-title: J Nat Prod doi: 10.1021/np030096l – volume: 78 start-page: 7603 issue: 22 year: 2006 end-page: 7609 ident: CR33 article-title: Biosensing systems for the detection of bacterial quorum signaling molecules publication-title: Anal Chem doi: 10.1021/ac061421n – ident: CR10 – volume: 183 start-page: 270 issue: 1 year: 2001 end-page: 279 ident: CR38 article-title: Transcriptional organization and dynamic expression of the hbpCAD genes, which encode the first three enzymes for 2-hydroxybiphenyl degradation in Pseudomonas azelaica HBP1 publication-title: J Bacteriol doi: 10.1128/JB.183-1.270-279.2001 – volume: 26 start-page: 3647 issue: 8 year: 2011 end-page: 3653 ident: CR14 article-title: A portable bioluminescence engineered cell-based biosensor for on-site applications publication-title: Biosens Bioelectron doi: 10.1016/j.bios.2011.02.022 – volume: 75 start-page: 4875 issue: 10 year: 2007 end-page: 4884 ident: CR21 article-title: Global effects of the cell-to-cell signaling molecules autoinducer-2, autoinducer-3, and epinephrine in a luxs mutant of enterohemorrhagic Escherichia coli publication-title: Infect Immun doi: 10.1128/IAI.00550-07 – volume: 30 start-page: 77 issue: 2 year: 2007 end-page: 81 ident: CR49 article-title: Development of bacterial biosensor for detecting organomercurials using organomercurial lyase gene and bioluminescence reporter system publication-title: J Japan Soc Water Environ doi: 10.2965/jswe.30.77 – volume: 48 start-page: 1112 issue: 4 year: 2004 end-page: 1117 ident: CR54 article-title: In vivo detection and quantification of Tetracycline by use of a whole-cell biosensor in the rat intestine publication-title: Antimicrob Agents Chemother doi: 10.1128/AAC.48.4.1112-1117.2004 – volume: 400 start-page: 1041 issue: 4 year: 2011 end-page: 1049 ident: CR13 article-title: Luminescent bacteria-based sensing method for methylmercury specific determination publication-title: Anal Bioanal Chem doi: 10.1007/s00216-011-4866-x – volume: 100 start-page: 8951 issue: 15 year: 2003 end-page: 8956 ident: CR20 article-title: Bacteria–host communication: The language of hormones publication-title: Proc Natl Acad Sci doi: 10.1073/pnas.1537100100 – volume: 208 start-page: 155 issue: 5006 year: 1965 end-page: 159 ident: CR15 article-title: Control of the competent state in Pneumococcus by a hormone-like cell product: an example for a new type of regulatory mechanism in bacteria publication-title: Nature doi: 10.1038/208155a0 – volume: 207 start-page: 1 issue: 1 year: 2002 end-page: 7 ident: CR29 article-title: Direct detection of N-acyl homoserine lactones in cystic fibrosis sputum publication-title: FEMS Microbiol Lett doi: 10.1111/j.1574-6968.2002.tb11019.x – volume: 79 start-page: 5740 issue: 15 year: 2007 end-page: 5745 ident: CR39 article-title: Hydroxylated polychlorinated biphenyl detection based on a genetically engineered bioluminescent whole-cell sensing system publication-title: Anal Chem doi: 10.1021/ac0705162 – volume: 94 start-page: 1087 issue: 6 year: 2003 end-page: 1097 ident: CR53 article-title: Influence of tetracycline exposure on tetracycline resistance and the carriage of tetracycline resistance genes within commensal Escherichia coli populations publication-title: J Appl Microbiol doi: 10.1046/j.1365-2672.2003.01937.x – volume: 73 start-page: 5168 issue: 21 year: 2001 end-page: 5171 ident: CR52 article-title: Detection of organomercurials with sensor bacteria publication-title: Anal Chem doi: 10.1021/ac010550v – volume: 250 start-page: 105 issue: 1 year: 2005 end-page: 110 ident: CR57 article-title: Bioluminescence-mediated stimulation of photoreactivation in bacteria publication-title: FEMS Microbiol Lett doi: 10.1016/j.femsle.2005.06.047 – volume: 407 start-page: 762 issue: 6805 year: 2000 end-page: 764 ident: CR32 article-title: Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms publication-title: Nature doi: 10.1038/35037627 – volume: 430 start-page: 109 issue: 6995 year: 2004 end-page: 115 ident: CR64 article-title: Drug discovery: The leading edge publication-title: Nature doi: 10.1038/430109a – volume: 73 start-page: 3197 issue: 6 year: 2005 end-page: 3209 ident: CR23 article-title: Bacterial cell-to-cell signaling in the gastrointestinal tract publication-title: Infect Immun doi: 10.1128/IAI.73.6.3197-3209.2005 – volume: 17 start-page: 90 year: 2009 end-page: 95 ident: CR11 article-title: Sposensor: A whole-bacterial biosensor that uses immobilized Bacillus subtilis spores and a one-step incubation/detection process publication-title: J Mol Microbiol Biotechnol doi: 10.1159/000206634 – volume: 244 start-page: 297 issue: 2 year: 2005 end-page: 304 ident: CR3 article-title: Identification of N-acyl homoserine lactones in mucopurulent respiratory secretions from cystic fibrosis patients publication-title: FEMS Microbiol Lett doi: 10.1016/j.femsle.2005.01.055 – volume: 14 start-page: 90 issue: 1 year: 2004 end-page: 98 ident: CR59 article-title: Identification of antibiotic stress-inducible promoters: a systematic approach to novel pathway-specific reporter assays for antibacterial drug discovery publication-title: Genome Res doi: 10.1101/gr.1275704 – volume: 48 start-page: 2838 issue: 8 year: 2004 end-page: 2844 ident: CR62 article-title: Prediction of mechanisms of action of antibacterial compounds by gene expression profiling publication-title: Antimicrob Agents Chemother doi: 10.1128/AAC.48.8.2838-2844.2004 – volume: 430 start-page: 109 issue: 6995 year: 2004 ident: 5756_CR64 publication-title: Nature doi: 10.1038/430109a – ident: 5756_CR22 – volume: 9 start-page: 504 issue: 7 year: 1995 ident: 5756_CR40 publication-title: FASEB J doi: 10.1096/fasebj.9.7.7737458 – volume: 30 start-page: 92 issue: 1 year: 2009 ident: 5756_CR47 publication-title: Electrophoresis doi: 10.1002/elps.200800382 – volume: 4 start-page: 67 issue: 2 year: 1999 ident: 5756_CR63 publication-title: J Biomol Screen doi: 10.1177/108705719900400206 – volume: 400 start-page: 1041 issue: 4 year: 2011 ident: 5756_CR13 publication-title: Anal Bioanal Chem doi: 10.1007/s00216-011-4866-x – volume: 57 start-page: 139 issue: 2 year: 1985 ident: 5756_CR43 publication-title: Arch Toxicol doi: 10.1007/BF00343125 – ident: 5756_CR26 – volume: 21 start-page: 149 issue: 2 year: 2006 ident: 5756_CR44 publication-title: Indian J Clin Biochem doi: 10.1007/BF02912931 – volume: 207 start-page: 1 issue: 1 year: 2002 ident: 5756_CR29 publication-title: FEMS Microbiol Lett doi: 10.1111/j.1574-6968.2002.tb11019.x – volume: 78 start-page: 6692 issue: 19 year: 2006 ident: 5756_CR7 publication-title: Anal Chem doi: 10.1021/ac069464r – volume: 55 start-page: 165 issue: 1 year: 2001 ident: 5756_CR16 publication-title: Annu Rev Microbiol doi: 10.1146/annurev.micro.55.1.165 – volume: 73 start-page: 5168 issue: 21 year: 2001 ident: 5756_CR52 publication-title: Anal Chem doi: 10.1021/ac010550v – ident: 5756_CR8 – volume: 94 start-page: 1087 issue: 6 year: 2003 ident: 5756_CR53 publication-title: J Appl Microbiol doi: 10.1046/j.1365-2672.2003.01937.x – volume: 407 start-page: 762 issue: 6805 year: 2000 ident: 5756_CR32 publication-title: Nature doi: 10.1038/35037627 – volume: 112 start-page: 1300 issue: 9 year: 2003 ident: 5756_CR17 publication-title: J Clin Invest doi: 10.1172/JCI20074 – volume: 20 start-page: 107 issue: 1 year: 1997 ident: 5756_CR51 publication-title: Biol Pharm Bull doi: 10.1248/bpb.20.107 – volume: 49 start-page: 749 issue: 2 year: 2005 ident: 5756_CR60 publication-title: Antimicrob Agents Chemother doi: 10.1128/AAC.49.2.749-759.2005 – volume: 46 start-page: 142 issue: 2 year: 2000 ident: 5756_CR50 publication-title: J Heal Sci doi: 10.1248/jhs.46.142 – volume: 9 start-page: 773 issue: 4 year: 1993 ident: 5756_CR19 publication-title: Mol Microbiol doi: 10.1111/j.1365-2958.1993.tb01737.x – volume: 386 start-page: 1025 issue: 4 year: 2006 ident: 5756_CR1 publication-title: Anal Bioanal Chem doi: 10.1007/s00216-006-0574-3 – volume: 30 start-page: 541 issue: 3 year: 2011 ident: 5756_CR2 publication-title: Trends Anal Chem doi: 10.1016/j.trac.2011.01.006 – volume: 100 start-page: 8951 issue: 15 year: 2003 ident: 5756_CR20 publication-title: Proc Natl Acad Sci doi: 10.1073/pnas.1537100100 – volume: 72 start-page: 939 issue: 5 year: 1993 ident: 5756_CR28 publication-title: J Dent Res doi: 10.1177/00220345930720051601 – volume: 70 start-page: 1783 issue: 4 year: 2002 ident: 5756_CR30 publication-title: Infect Immun doi: 10.1128/IAI.70.4.1783-1790.2002 – volume: 279 start-page: 26066 issue: 25 year: 2004 ident: 5756_CR66 publication-title: J Biol Chem doi: 10.1074/jbc.M402989200 – volume: 74 start-page: 5445 issue: 10 year: 2006 ident: 5756_CR24 publication-title: Infect Immun doi: 10.1128/IAI.00099-06 – volume: 48 start-page: 1112 issue: 4 year: 2004 ident: 5756_CR54 publication-title: Antimicrob Agents Chemother doi: 10.1128/AAC.48.4.1112-1117.2004 – volume: 48 start-page: 2588 issue: 7 year: 2004 ident: 5756_CR61 publication-title: Antimicrob Agents Chemother doi: 10.1128/AAC.48.7.2588-2594.2004 – volume: 82 start-page: 4457 issue: 11 year: 2010 ident: 5756_CR35 publication-title: Anal Chem doi: 10.1021/ac100231a – volume: 183 start-page: 270 issue: 1 year: 2001 ident: 5756_CR38 publication-title: J Bacteriol doi: 10.1128/JB.183-1.270-279.2001 – volume: 25 start-page: 1529 issue: 9 year: 2009 ident: 5756_CR42 publication-title: World J Microbiol Biotechnol doi: 10.1007/s11274-009-0050-2 – volume: 60 start-page: 539 issue: 3 year: 1996 ident: 5756_CR31 publication-title: Microbiol Rev doi: 10.1128/MMBR.60.3.539-574.1996 – volume: 18 start-page: 135 issue: 2 year: 2011 ident: 5756_CR6 publication-title: Environ Sci Pollut Res doi: 10.1007/s11356-010-0392-1 – volume: 75 start-page: 4875 issue: 10 year: 2007 ident: 5756_CR21 publication-title: Infect Immun doi: 10.1128/IAI.00550-07 – volume: 34 start-page: 29 issue: 1 year: 2001 ident: 5756_CR41 publication-title: Anal Lett doi: 10.1081/AL-100002702 – volume: 10 start-page: 4558 issue: 5 year: 2010 ident: 5756_CR4 publication-title: Sens doi: 10.3390/s100504558 – volume: 244 start-page: 297 issue: 2 year: 2005 ident: 5756_CR3 publication-title: FEMS Microbiol Lett doi: 10.1016/j.femsle.2005.01.055 – volume: 20 start-page: 10 issue: 1 year: 2009 ident: 5756_CR5 publication-title: Semin Cell Dev Biol doi: 10.1016/j.semcdb.2009.01.010 – volume: 56 start-page: 1862 issue: 12 year: 2010 ident: 5756_CR56 publication-title: Clin Chem doi: 10.1373/clinchem.2010.145581 – volume: 66 start-page: 1022 issue: 7 year: 2003 ident: 5756_CR65 publication-title: J Nat Prod doi: 10.1021/np030096l – volume: 17 start-page: 90 year: 2009 ident: 5756_CR11 publication-title: J Mol Microbiol Biotechnol doi: 10.1159/000206634 – start-page: 35 volume-title: PCBs, recent advances in environmental toxicology and health effects year: 2001 ident: 5756_CR36 – volume: 250 start-page: 105 issue: 1 year: 2005 ident: 5756_CR57 publication-title: FEMS Microbiol Lett doi: 10.1016/j.femsle.2005.06.047 – volume: 73 start-page: 3197 issue: 6 year: 2005 ident: 5756_CR23 publication-title: Infect Immun doi: 10.1128/IAI.73.6.3197-3209.2005 – volume: 30 start-page: 77 issue: 2 year: 2007 ident: 5756_CR49 publication-title: J Japan Soc Water Environ doi: 10.2965/jswe.30.77 – volume: 79 start-page: 5740 issue: 15 year: 2007 ident: 5756_CR39 publication-title: Anal Chem doi: 10.1021/ac0705162 – volume: 26 start-page: 3647 issue: 8 year: 2011 ident: 5756_CR14 publication-title: Biosens Bioelectron doi: 10.1016/j.bios.2011.02.022 – volume: 14 start-page: 90 issue: 1 year: 2004 ident: 5756_CR59 publication-title: Genome Res doi: 10.1101/gr.1275704 – volume: 41 start-page: 591 issue: 6 year: 2006 ident: 5756_CR46 publication-title: Appl Spectrosc Rev doi: 10.1080/05704920600929415 – volume: 163 start-page: 185 issue: 2 year: 1998 ident: 5756_CR27 publication-title: FEMS Microbiol Lett doi: 10.1111/j.1574-6968.1998.tb13044.x – volume: 92 start-page: 1490 issue: 5 year: 1995 ident: 5756_CR34 publication-title: Proc Natl Acad Sci doi: 10.1073/pnas.92.5.1490 – volume: 6 start-page: e19520 issue: 5 year: 2011 ident: 5756_CR37 publication-title: PLoS One doi: 10.1371/journal.pone.0019520 – volume: 73 start-page: 6436 issue: 20 year: 2007 ident: 5756_CR55 publication-title: Appl Environ Microbiol doi: 10.1128/AEM.00586-07 – volume: 48 start-page: 2838 issue: 8 year: 2004 ident: 5756_CR62 publication-title: Antimicrob Agents Chemother doi: 10.1128/AAC.48.8.2838-2844.2004 – volume: 43 start-page: 377 issue: 3 year: 2002 ident: 5756_CR58 publication-title: J Appl Genet – ident: 5756_CR10 – volume: 35 start-page: 231 issue: 2 year: 2010 ident: 5756_CR48 publication-title: J Toxicol Sci doi: 10.2131/jts.35.231 – volume: 35 start-page: 69 issue: 2 year: 2009 ident: 5756_CR18 publication-title: Crit Rev Microbiol doi: 10.1080/10408410902733946 – volume: 78 start-page: 7603 issue: 22 year: 2006 ident: 5756_CR33 publication-title: Anal Chem doi: 10.1021/ac061421n – ident: 5756_CR9 doi: 10.1007/b13533 – volume: 67 start-page: 5854 issue: 11 year: 1999 ident: 5756_CR25 publication-title: Infect Immun doi: 10.1128/IAI.67.11.5854-5862.1999 – volume: 26 start-page: 67 issue: 1 year: 2006 ident: 5756_CR45 publication-title: Clin Lab Med doi: 10.1016/j.cll.2006.02.003 – volume: 208 start-page: 155 issue: 5006 year: 1965 ident: 5756_CR15 publication-title: Nature doi: 10.1038/208155a0 – volume: 659 start-page: 122 issue: 1–2 year: 2010 ident: 5756_CR12 publication-title: Anal Chim Acta doi: 10.1016/j.aca.2009.11.027
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SubjectTerms	Analysis Analytical Chemistry Animals Antibacterial agents Assessments Bacteria Bacteria - genetics Bacterial Physiological Phenomena Biochemistry Biomedical Research Biosensing Techniques - instrumentation Biosensing Techniques - methods Characterization and Evaluation of Materials Chemistry Chemistry and Materials Science Cost analysis Detection Food Science Genes, Reporter Genetic Engineering Genomes Humans Laboratory Medicine Mathematical analysis Miniaturization Monitoring/Environmental Analysis Plasmids - genetics Plasmids - metabolism Proteins Quorum Sensing Review Screening Technology application
Title	Engineered cells as biosensing systems in biomedical analysis
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