Genome editing with CRISPR-Cas nucleases, base editors, transposases and prime editors

The development of new CRISPR-Cas genome editing tools continues to drive major advances in the life sciences. Four classes of CRISPR-Cas-derived genome editing agents-nucleases, base editors, transposases/recombinases and prime editors-are currently available for modifying genomes in experimental s...

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Bibliographic Details

Published in:	Nature biotechnology Vol. 38; no. 7; pp. 824 - 844
Main Authors:	Anzalone, Andrew V, Koblan, Luke W, Liu, David R
Format:	Journal Article
Language:	English
Published:	United States Nature Publishing Group 01.07.2020
Subjects:	CRISPR CRISPR-Cas Systems - genetics DNA Breaks, Double-Stranded Editing Endonucleases - genetics Gene Editing - methods Genome - genetics Genome editing Genomes Humans Nuclease Recombinases - genetics Transposases - genetics
ISSN:	1087-0156, 1546-1696, 1546-1696
Online Access:	Get full text
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