Autologous Mesenchymal Stem Cells, Applied in a Bioabsorbable Matrix, for Treatment of Perianal Fistulas in Patients With Crohn's Disease

In patients with Crohn's disease, perianal fistulas recur frequently, causing substantial morbidity. We performed a 12-patient, 6-month, phase 1 trial to determine whether autologous mesenchymal stem cells, applied in a bioabsorbable matrix, can heal the fistula. Fistula repair was not associat...

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Vydané v:	Gastroenterology (New York, N.Y. 1943) Ročník 153; číslo 1; s. 59
Hlavní autori:	Dietz, Allan B, Dozois, Eric J, Fletcher, Joel G, Butler, Greg W, Radel, Darcie, Lightner, Amy L, Dave, Maneesh, Friton, Jessica, Nair, Asha, Camilleri, Emily T, Dudakovic, Amel, van Wijnen, Andre J, Faubion, William A
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.07.2017
Predmet:	Absorbable Implants - adverse effects Adolescent Adult Crohn Disease - complications Cutaneous Fistula - etiology Cutaneous Fistula - therapy Female Humans Male Mesenchymal Stem Cell Transplantation - adverse effects Middle Aged Rectal Fistula - etiology Rectal Fistula - therapy Transplantation, Autologous Treatment Outcome Wound Healing Young Adult IBD Cell Therapy Clinical Trial STOMP Trial
ISSN:	1528-0012, 1528-0012
On-line prístup:	Zistit podrobnosti o prístupe
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