Obesity: a perfect storm for carcinogenesis

Obesity-related cancers account for 40% of the cancer cases observed in the USA and obesity is overtaking smoking as the most widespread modifiable risk factor for carcinogenesis. Here, we use the hallmarks of cancer framework to delineate how obesity might influence the carcinogenic hallmarks in so...

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Bibliographic Details
Published in:	Cancer and metastasis reviews Vol. 41; no. 3; pp. 491 - 515
Main Authors:	Harris, Benjamin H. L., Macaulay, Valentine M., Harris, David A., Klenerman, Paul, Karpe, Fredrik, Lord, Simon R., Harris, Adrian L., Buffa, Francesca M.
Format:	Journal Article
Language:	English
Published:	New York Springer US 01.09.2022 Springer Springer Nature B.V
Subjects:	Angiogenesis Biomedical and Life Sciences Biomedicine Cancer Research Carcinogenesis Cell death Energy metabolism Genomes Genomic instability Humans Inflammation Malignancy Metastases Neoplasms - metabolism Neovascularization, Pathologic - pathology Obesity Obesity - complications Oncology Patients Physiological aspects Risk factors Signal Transduction Somatic cells Tumors Obesity Hallmarks of cancer Adiposity Carcinogenesis Cancer BMI
ISSN:	0167-7659, 1573-7233, 1573-7233
Online Access:	Get full text
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