Evaluation of T cell responses to naturally processed variant SARS-CoV-2 spike antigens in individuals following infection or vaccination

Most existing studies characterizing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific T cell responses are peptide based. This does not allow evaluation of whether tested peptides are processed and presented canonically. In this study, we use recombinant vaccinia virus (rVACV)-m...

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Veröffentlicht in:	Cell reports (Cambridge) Jg. 42; H. 5; S. 112470
Hauptverfasser:	Yin, Zixi, Chen, Ji-Li, Lu, Yongxu, Wang, Beibei, Godfrey, Leila, Mentzer, Alexander J., Yao, Xuan, Liu, Guihai, Wellington, Dannielle, Zhao, Yiqi, Wing, Peter A.C., Dejnirattisa, Wanwisa, Supasa, Piyada, Liu, Chang, Hublitz, Philip, Beveridge, Ryan, Waugh, Craig, Clark, Sally-Ann, Clark, Kevin, Sopp, Paul, Rostron, Timothy, Mongkolsapaya, Juthathip, Screaton, Gavin R., Ogg, Graham, Ewer, Katie, Pollard, Andrew J., Gilbert, Sarah, Knight, Julian C., Lambe, Teresa, Smith, Geoffrey L., Dong, Tao, Peng, Yanchun
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Elsevier Inc 30.05.2023 Cell Press Elsevier
Schlagworte:	Antibodies, Viral antigen processing and presentation ChAdOx1 nCoV-19 COVID-19 CP: Immunology Humans immune escape recombinant vaccinia virus SARS-CoV-2 spike protein T cell Vaccination variants of concern CP: Immunology SARS-CoV-2 variants of concern T cell spike protein recombinant vaccinia virus antigen processing and presentation immune escape ChAdOx1 nCoV-19
ISSN:	2211-1247, 2211-1247
Online-Zugang:	Volltext
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