Neurogenesis and progenitor cell distribution in the subgranular zone and subventricular zone of the adult sheep brain

•We studied adult sheep neurogenic niches after administering BrdU.•Progenitor cell distribution in the sheep subventricular zone is similar to humans.•The sheep subventricular zone has far more progenitors than the hippocampus.•The overall structure of the sheep subventricular zone is similar to hu...

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Bibliographic Details
Published in:	Neuroscience Vol. 244; pp. 173 - 187
Main Authors:	Low, V.F., Faull, R.L.M., Bennet, L., Gunn, A.J., Curtis, M.A.
Format:	Journal Article
Language:	English
Published:	Amsterdam Elsevier Ltd 06.08.2013 Elsevier
Subjects:	Age Factors animal model Animals Biological and medical sciences Brain - cytology Brain - growth & development brain plasticity Cell Proliferation Female Fundamental and applied biological sciences. Psychology germinal niche Neurogenesis Neurology Sheep Stem Cells - cytology Stem Cells - physiology transgenic sheep Vertebrates: nervous system and sense organs PBS DG PCNA DAB TBS transgenic sheep EL SGZ CN GFAP GCL TBS-T germinal niche NeuN SVZ neurogenesis RMS HD animal model BrdU brain plasticity caudate nucleus neuronal nuclear antigen 5-bromo-2′-deoxyuridine phosphate-buffered saline tris-buffered saline with Triton X-100 Huntington’s disease rostral migratory stream subventricular zone 3,3-diaminobenzidine granule cell layer subgranular zone proliferating cell nuclear antigen dentate gyrus tris-buffered saline ependymal layer glial fibrillary acidic protein Animal model Central nervous system Precursor cell Transgenic animal Neurogenesis Encephalon Vertebrata Mammalia Distribution Plasticity Sheep Artiodactyla Ungulata Progenitor cell
ISSN:	0306-4522, 1873-7544, 1873-7544
Online Access:	Get full text
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