Endoplasmic Reticulum (ER) Stress and Endocrine Disorders

The endoplasmic reticulum (ER) is the organelle where secretory and membrane proteins are synthesized and folded. Unfolded proteins that are retained within the ER can cause ER stress. Eukaryotic cells have a defense system called the “unfolded protein response” (UPR), which protects cells from ER s...

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Veröffentlicht in:	International journal of molecular sciences Jg. 18; H. 2; S. 382
Hauptverfasser:	Ariyasu, Daisuke, Yoshida, Hiderou, Hasegawa, Yukihiro
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Switzerland MDPI AG 11.02.2017 MDPI
Schlagworte:	Animals Diabetes Disease Models, Animal Endocrine System Diseases - diagnosis Endocrine System Diseases - etiology Endocrine System Diseases - metabolism Endocrine System Diseases - therapy Endoplasmic reticulum Endoplasmic Reticulum Stress Humans Mammals Review Signal Transduction Unfolded Protein Response endocrine disorder old astrocyte specifically induced substance (OASIS) family chemical chaperone PKR-like endoplasmic reticulum kinase (PERK) inositol requirement 1 (IRE1) activating transcription factor 6 (ATF6) endoplasmic reticulum stress
ISSN:	1422-0067, 1661-6596, 1422-0067
Online-Zugang:	Volltext
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