Heat shock protein 60 levels in tissue and circulating exosomes in human large bowel cancer before and after ablative surgery

BACKGROUND Heat shock protein 60 (Hsp60) is a chaperonin involved in tumorigenesis, but its participation in tumor development and progression is not well understood and its value as a tumor biomarker has not been fully elucidated. In the current study, the authors presented evidence supporting the...

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Vydané v:	Cancer Ročník 121; číslo 18; s. 3230 - 3239
Hlavní autori:	Campanella, Claudia, Rappa, Francesca, Sciumè, Carmelo, Marino Gammazza, Antonella, Barone, Rosario, Bucchieri, Fabio, David, Sabrina, Curcurù, Giuseppe, Caruso Bavisotto, Celeste, Pitruzzella, Alessandro, Geraci, Girolamo, Modica, Giuseppe, Farina, Felicia, Zummo, Giovanni, Fais, Stefano, Conway de Macario, Everly, Macario, Alberto J.L., Cappello, Francesco
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 15.09.2015
Predmet:	Adenocarcinoma - metabolism Adenocarcinoma - pathology Adenocarcinoma - surgery Aged Aged, 80 and over Biomarkers, Tumor - analysis Blotting, Western Chaperonin 60 - analysis Chaperonin 60 - metabolism colon adenocarcinoma Colonic Neoplasms - metabolism Colonic Neoplasms - pathology Colonic Neoplasms - surgery Enzyme-Linked Immunosorbent Assay exosomes Exosomes - metabolism Female heat shock protein 60 (Hsp60) Humans Immunohistochemistry macrophages Male Middle Aged Mitochondrial Proteins - analysis Mitochondrial Proteins - metabolism natural killer cells plasma cell membrane Real-Time Polymerase Chain Reaction theranostics heat shock protein 60 (Hsp60) plasma cell membrane natural killer cells macrophages colon adenocarcinoma exosomes theranostics
ISSN:	0008-543X, 1097-0142
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