Intravascular Mesenchymal Stromal/Stem Cell Therapy Product Diversification: Time for New Clinical Guidelines

Intravascular infusion is the most popular route for therapeutic multipotent mesenchymal stromal/stem cell (MSC) delivery in hundreds of clinical trials. Meta-analysis has demonstrated that bone marrow MSC infusion is safe. It is not clear if this also applies to diverse new cell products derived fr...

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Veröffentlicht in:	Trends in molecular medicine Jg. 25; H. 2; S. 149 - 163
Hauptverfasser:	Moll, Guido, Ankrum, James A., Kamhieh-Milz, Julian, Bieback, Karen, Ringdén, Olle, Volk, Hans-Dieter, Geissler, Sven, Reinke, Petra
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Elsevier Ltd 01.02.2019
Schlagworte:	Animals CD142 cellular therapy Clinical Trials as Topic hemocompatibility Humans Inflammation - etiology Inflammation - immunology Mesenchymal Stem Cell Transplantation - adverse effects Mesenchymal Stem Cell Transplantation - methods Mesenchymal Stem Cells - cytology Mesenchymal Stem Cells - immunology mesenchymal stromal/stem cell safety and efficacy Thromboplastin - analysis Thromboplastin - immunology tissue factor tissue source CD142 hemocompatibility tissue factor safety and efficacy cellular therapy mesenchymal stromal/stem cell tissue source
ISSN:	1471-4914, 1471-499X, 1471-499X
Online-Zugang:	Volltext
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