Influence of APOE-2 genotype on the relation between adiposity and plasma lipid levels in patients with vascular disease

Background: Apolipoprotein E ( APOE ) genotypes are associated with different plasma lipid levels. People with the APO ɛ2 genotype can develop a disorder called dysbetalipoproteinemia (DBL). A possible predisposing factor for DBL is adiposity. We evaluated whether and to what extent the APOE genotyp...

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Bibliographic Details
Published in:	International Journal of Obesity Vol. 39; no. 2; pp. 265 - 269
Main Authors:	Koopal, C, van der Graaf, Y, Asselbergs, F W, Westerink, J, Visseren, F L J
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 01.02.2015 Nature Publishing Group
Subjects:	631/208/205 692/308/174 692/699/2743/393 692/699/75/2099 692/699/75/593 Abdomen Adipose tissue Adiposity - genetics Analysis Apolipoprotein E Apolipoprotein E2 - genetics Apolipoprotein E2 - metabolism Apolipoproteins Blood circulation disorders Blood lipids Body fat Body Fat Distribution Body Mass Index Body size Cardiovascular disease Causes of Cholesterol Cohort analysis Complications and side effects Confidence intervals Dependent variables Epidemiology Evaluation Female Genetic aspects Genetic Predisposition to Disease - genetics Genotype Genotype & phenotype Genotypes Health Promotion and Disease Prevention Health risk assessment Health sciences Heterozygotes High density lipoprotein Homozygotes Humans Hyperlipoproteinemia Type III - genetics Hyperlipoproteinemia Type III - metabolism Hyperlipoproteinemia Type III - physiopathology Internal Medicine Lipid metabolism Lipids Lipids - blood Lipids - genetics Lipoproteins Male Medicine Medicine & Public Health Metabolic Diseases Metabolic disorders Metabolic syndrome Metabolic Syndrome - genetics Metabolic Syndrome - metabolism Middle Aged Obesity Obesity, Abdominal - genetics Obesity, Abdominal - metabolism original-article Patients Physiological aspects Plasma Prospective Studies Public Health Regression analysis Statistical analysis Vascular diseases Vascular Diseases - genetics Vascular Diseases - metabolism Vascular Diseases - physiopathology Vein & artery diseases Netherlands
ISSN:	0307-0565, 1476-5497, 1476-5497
Online Access:	Get full text
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