The Role of Racial and Ethnic Factors in MicroRNA Expression and Risk for Type 2 Diabetes

Prior studies focused on circulating microRNAs and the risk for complex diseases have shown inconsistent findings. The majority of studies focused on European and East Asian racial or ethnic groups, however, ancestry was not typically reported. We evaluated the risk for type 2 diabetes as an exempla...

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Published in:Frontiers in genetics Vol. 13; p. 853633
Main Authors: Flowers, Elena, Kanaya, Alka M., Zhang, Li, Aouizerat, Bradley E.
Format: Journal Article
Language:English
Published: Switzerland Frontiers Media S.A 18.03.2022
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ISSN:1664-8021, 1664-8021
Online Access:Get full text
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Summary:Prior studies focused on circulating microRNAs and the risk for complex diseases have shown inconsistent findings. The majority of studies focused on European and East Asian racial or ethnic groups, however, ancestry was not typically reported. We evaluated the risk for type 2 diabetes as an exemplar to show that race and ethnic group may contribute to inconsistent validation of previous findings of associations with microRNAs.
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Reviewed by: Mehmet Taşpinar, Aksaray University, Turkey
Burak Barut, Karadeniz Technical University, Turkey
Edited by: Yusuf Tutar, University of Health Sciences (Turkey), Turkey
This article was submitted to RNA, a section of the journal Frontiers in Genetics
ISSN:1664-8021
1664-8021
DOI:10.3389/fgene.2022.853633