The Role of Racial and Ethnic Factors in MicroRNA Expression and Risk for Type 2 Diabetes

Prior studies focused on circulating microRNAs and the risk for complex diseases have shown inconsistent findings. The majority of studies focused on European and East Asian racial or ethnic groups, however, ancestry was not typically reported. We evaluated the risk for type 2 diabetes as an exempla...

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Vydáno v:Frontiers in genetics Ročník 13; s. 853633
Hlavní autoři: Flowers, Elena, Kanaya, Alka M., Zhang, Li, Aouizerat, Bradley E.
Médium: Journal Article
Jazyk:angličtina
Vydáno: Switzerland Frontiers Media S.A 18.03.2022
Témata:
biomarker
diabetes
fasting blood glucose
Genetics
microRNA
prediabetes
race/ethnicity
fasting blood glucose
ancestry
prediabetes
microRNA
diabetes prevention program
biomarker
diabetes
race/ethnicity
ISSN:1664-8021, 1664-8021
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Shrnutí:Prior studies focused on circulating microRNAs and the risk for complex diseases have shown inconsistent findings. The majority of studies focused on European and East Asian racial or ethnic groups, however, ancestry was not typically reported. We evaluated the risk for type 2 diabetes as an exemplar to show that race and ethnic group may contribute to inconsistent validation of previous findings of associations with microRNAs.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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Reviewed by: Mehmet Taşpinar, Aksaray University, Turkey
Burak Barut, Karadeniz Technical University, Turkey
Edited by: Yusuf Tutar, University of Health Sciences (Turkey), Turkey
This article was submitted to RNA, a section of the journal Frontiers in Genetics
ISSN:1664-8021
1664-8021
DOI:10.3389/fgene.2022.853633