Differential effects of ceramide species on exocytosis in rat PC12 cells

Increases in several ceramide species have been shown by non-targeted lipid profiling (lipidomics) of the rat hippocampus after kainate lesions (Guan et al. FASEB J 20:1152-1161, 2006). This study was carried out to examine possible effects of ceramide species on exocytosis. Significant increase in...

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Veröffentlicht in:	Experimental brain research Jg. 183; H. 2; S. 241 - 247
Hauptverfasser:	Tang, Ning, Ong, Wei-Yi, Zhang, En-Ming, Chen, Peng, Yeo, Jin-Fei
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Berlin Springer 01.11.2007 Springer Nature B.V
Schlagworte:	Anatomy Animals Arachnids beta-Cyclodextrins - pharmacology Biological and medical sciences Cell culture Cell Membrane - drug effects Central nervous system Ceramides - classification Ceramides - pharmacology Cholesterol Drug Interactions Electric Capacitance Exocytosis - drug effects Experiments Fatty acids Fundamental and applied biological sciences. Psychology Green Fluorescent Proteins - metabolism Hippocampus Lesions Lipids Membrane Microdomains - drug effects Microscopy Microscopy, Fluorescence - methods Morality Motor control and motor pathways. Reflexes. Control centers of vegetative functions. Vestibular system and equilibration Neurons Neuropeptide Y - metabolism Patch-Clamp Techniques PC12 Cells - drug effects Profiles Rats Time Factors Vertebrates: nervous system and sense organs United States > US Singapore Lipid raft Membrane capacitance Rat Rodentia Central nervous system Glutamatergic neuron Fluorescence Sphingolipid Glutamate Exocytosis Protein Encephalon Vertebrata Mammalia Synaptic transmission Total internal reflection fluorescence microscopy Excitotoxicity Excitatory aminoacid Neurotransmitter Ceramide Hippocampus
ISSN:	0014-4819, 1432-1106
Online-Zugang:	Volltext
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