Detection and characterization of a divergent avian reovirus strain from a broiler chicken with central nervous system disease

Avian orthoreoviruses have been associated with a variety of diseases in chickens, including tenosynovitis, runting-stunting syndrome, hepatitis, myocarditis, osteoporosis, respiratory diseases, and central nervous system disease. The primary objective of our study was the molecular characterization...

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Bibliographic Details
Published in:Archives of virology Vol. 158; no. 12; pp. 2583 - 2588
Main Authors: Dandár, Eszter, Bálint, Ádám, Kecskeméti, Sándor, Szentpáli-Gavallér, Katalin, Kisfali, Péter, Melegh, Béla, Farkas, Szilvia L, Bányai, Krisztián
Format: Journal Article
Language:English
Published: Vienna Springer-Verlag 01.12.2013
Springer Vienna
Springer Nature B.V
Subjects:
Animals
Avian orthoreovirus
Avian reovirus
Biomedical and Life Sciences
Biomedicine
Brief Report
broiler chickens
cell culture
central nervous system
Central Nervous System Infections
Central Nervous System Infections - veterinary
Central Nervous System Infections - virology
Chickens
Cluster Analysis
Food chains
Genes
genetic background
genetics
Genome, Viral
Genomes
Hepatitis
Hungary
Infectious Diseases
isolation & purification
Medical Microbiology
Myocarditis
Nervous system
Neurological disorders
nucleic acids
nucleotide sequences
Orthoreovirus, Avian
Orthoreovirus, Avian - genetics
Orthoreovirus, Avian - isolation & purification
Osteoporosis
Phylogenetics
Phylogeny
Poultry
Poultry Diseases
Poultry Diseases - virology
Reoviridae Infections
Reoviridae Infections - veterinary
Reoviridae Infections - virology
Reovirus
Respiratory diseases
respiratory tract diseases
RNA, Viral
RNA, Viral - genetics
sequence analysis
Sequence Analysis, DNA
Sequence Homology, Nucleic Acid
tenosynovitis
veterinary
Virology
Hungary
Phylogenetic analysis
Genome sequencing
Hungary
ISSN:0304-8608, 1432-8798, 1432-8798
Online Access:Get full text
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Summary:Avian orthoreoviruses have been associated with a variety of diseases in chickens, including tenosynovitis, runting-stunting syndrome, hepatitis, myocarditis, osteoporosis, respiratory diseases, and central nervous system disease. The primary objective of our study was the molecular characterization of an avian reovirus strain, T1781, which was isolated from a broiler chicken with a central nervous system disorder in Hungary during 2012. The complete genome sequence was determined using a traditional sequencing method after cell culture adaptation of the strain. Sequence and phylogenetic analyses showed that T1781 shared only moderate nucleic acid sequence identity in several genes to previously analyzed reovirus strains from chickens, and each gene formed separate branches in the corresponding phylogenetic trees. The maximum nucleotide sequence identities of strain T1781 genes to reference avian reovirus strains ranged from 79 % to 90 %. Collectively, our analyses indicated that T1781 is a divergent chicken reovirus strain. The genetic background of this and other avian reoviruses associated with various disease manifestations needs further investigation.
Bibliography:http://dx.doi.org/10.1007/s00705-013-1739-y
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ISSN:0304-8608
1432-8798
1432-8798
DOI:10.1007/s00705-013-1739-y