Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria

Mechanisms that regulate cellular metabolism are a fundamental requirement of all cells. Most eukaryotic cells rely on aerobic mitochondrial metabolism to generate ATP. Nevertheless, regulation of mitochondrial activity is incompletely understood. Here we identified an unexpected and essential role...

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Veröffentlicht in:	Cell Jg. 142; H. 2; S. 270
Hauptverfasser:	Cárdenas, César, Miller, Russell A, Smith, Ian, Bui, Thi, Molgó, Jordi, Müller, Marioly, Vais, Horia, Cheung, King-Ho, Yang, Jun, Parker, Ian, Thompson, Craig B, Birnbaum, Morris J, Hallows, Kenneth R, Foskett, J Kevin
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 23.07.2010
Schlagworte:	Animals Autophagy B-Lymphocytes - metabolism Calcium - metabolism Calcium Signaling Cell Line Chickens Gene Knockout Techniques Inositol 1,4,5-Trisphosphate Receptors - metabolism Mitochondria - metabolism Oxidative Phosphorylation
ISSN:	1097-4172, 1097-4172
Online-Zugang:	Weitere Angaben
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