Combined hyperforin and lanicemine treatment instead of ketamine or imipramine restores behavioral deficits induced by chronic restraint stress and dietary zinc restriction in mice

Clinical and preclinical studies show evidence that chronic stress or nutritional deficits in dietary zinc (Zn) intake may be risk factors for developing major depressive disorder (MDD). Furthermore, there may be possible links between low serum Zn levels and development of treatment-resistant depre...

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Bibliographic Details

Published in:	Frontiers in pharmacology Vol. 13; p. 933364
Main Authors:	Pochwat, Bartłomiej, Misztak, Paulina, Masternak, Julia, Bączyńska, Ewa, Bijata, Krystian, Roszkowska, Matylda, Bijata, Monika, Włodarczyk, Jakub, Szafarz, Małgorzata, Wyska, Elżbieta, Muszyńska, Bożena, Krakowska, Agata, Opoka, Włodzimierz, Nowak, Gabriel, Szewczyk, Bernadeta
Format:	Journal Article
Language:	English
Published:	Frontiers Media S.A 24.08.2022
Subjects:	chronic stress hyperforin and lanicemine ketamine Pharmacology refractory depression zinc deficiency
ISSN:	1663-9812, 1663-9812
Online Access:	Get full text
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