Influence of experimental parameters on in vitro human skin permeation of Bisphenol A

Bisphenol A (BPA) in vitro skin permeation studies have shown inconsistent results, which could be due to experimental conditions. We studied the impact of in vitro parameters on BPA skin permeation using flow-through diffusion cells with ex-vivo human skin (12 donors, 3–12 replicates). We varied sk...

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Bibliographic Details
Published in:	Toxicology in vitro Vol. 73; p. 105129
Main Authors:	Reale, E., Berthet, A., Wild, P., Vernez, D., Hopf, N.B.
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01.06.2021 Elsevier Science Ltd
Subjects:	Aqueous solutions Bisphenol A BPA Diffusion cells Exposure Human skin Mathematical analysis Parameters Penetration Percutaneous absorption Permeability Permeation constant Reduction Risk assessment Skin Skin thickness Thickness Vehicle volume Percutaneous absorption Human skin BPA Vehicle volume Skin thickness Permeation constant
ISSN:	0887-2333, 1879-3177, 1879-3177
Online Access:	Get full text
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