Optimizing ex vivo penetration tests via quantitative confocal Raman spectroscopy: Impact of incubation time, skin hydration, surfactant treatment and UVA irradiation on caffeine distribution

[Display omitted] Ex vivo penetration tests are important tools in cosmetic and pharmaceutical research. However, variability of experimental setups is challenging when reviewing literature. Different skin models, pre-treatments and experimental parameters render comparison difficult. Thus, our aim...

Full description

Saved in:

Bibliographic Details
Published in:	International journal of pharmaceutics Vol. 667; no. Pt B; p. 124932
Main Authors:	Steiner, Katja, Hübel, Pia, Srndic, Azra, Klang, Victoria
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 25.12.2024
Subjects:	Animals Caffeine Caffeine - pharmacokinetics Confocal Raman spectroscopy Humans Penetration Porcine ear skin quantitative CRS Skin - metabolism Skin - radiation effects Skin Absorption Sodium Dodecyl Sulfate - analogs & derivatives Sodium Dodecyl Sulfate - chemistry Spectrum Analysis, Raman - methods Surface-Active Agents - chemistry Surfactant Time Factors Ultraviolet Rays UVA Water - chemistry UVA SLES UV CRS quantitative CRS Surfactant SC Porcine ear skin Penetration PC PE NE Confocal Raman spectroscopy LPC PS80 Caffeine HLB MCT
ISSN:	0378-5173, 1873-3476, 1873-3476
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!