A case of catamenial erythema multiforme major successfully treated with goserelin

We report a case of catamenial erythema multiforme major in a 46-year-old female. She was treated successfully with goserelin, a GnRH agonist, until the expected age of menopause; however, its therapeutic effects persisted for longer than expected, possibly due to accumulation in adipose tissue. A g...

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Vydané v:	Endocrinology, diabetes & metabolism case reports Ročník 2023; číslo 4; s. 1 - 3
Hlavní autori:	Tyack, Lauren T, Stuckey, Bronwyn G A, Walsh, John P
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England Bioscientifica Ltd 01.10.2023 Bioscientifica
Predmet:	Adult Australia Female Gynaecological Endocrinology New Disease or Syndrome: Presentations/Diagnosis/Management Ovaries White
ISSN:	2052-0573, 2052-0573
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Shrnutí:	We report a case of catamenial erythema multiforme major in a 46-year-old female. She was treated successfully with goserelin, a GnRH agonist, until the expected age of menopause; however, its therapeutic effects persisted for longer than expected, possibly due to accumulation in adipose tissue. A group of menstrual cycle-related dermatoses and hypersensitivity syndromes exist but are rarely reported in the literature. A history of recurrent cutaneous eruptions in premenopausal females should be considered in the context of the menstrual cycle. The diagnosis of menstrual cycle-related dermatoses is largely clinical, although provocation testing can assist. Treatment options are broad and are aimed at reducing the immune response and/or suppressing ovulation. Goserelin may accumulate and have a gonadotrophin-suppressing effect for longer than expected.
Bibliografia:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	2052-0573 2052-0573
DOI:	10.1530/EDM-23-0030