Dopamine drives binge‐like consumption of a palatable food in experimental Parkinsonism

Background Prolonged dopaminergic replacement therapy in PD results in pulsatile dopamine receptors stimulation in both dorsal and ventral striatum causing wearing off, motor fluctuations, and nonmotor side effects such as behavioral addictions. Among impulse control disorders, binge eating can be e...

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Bibliographic Details
Published in:	Movement disorders Vol. 34; no. 6; pp. 821 - 831
Main Authors:	Mineo, Désirée, Cacace, Fabrizio, Mancini, Maria, Vannelli, Anna, Campanelli, Federica, Natale, Giuseppina, Marino, Gioia, Cardinale, Antonella, Calabresi, Paolo, Picconi, Barbara, Ghiglieri, Veronica
Format:	Journal Article
Language:	English
Published:	Hoboken, USA John Wiley & Sons, Inc 01.06.2019 Wiley Subscription Services, Inc
Subjects:	Addictions Animal behavior Animals Basal ganglia Behavioral plasticity Binge eating Body weight gain Brain diseases Central nervous system diseases Cortex Denervation Dihydroxyphenylalanine Dopamine Dopamine Agents - pharmacology Dopamine receptors Eating - drug effects Eating disorders Feeding Behavior - drug effects Food Food intake Food preferences Food Preferences - drug effects impulse control disorders Impulsive behavior Laboratory animals Levodopa Levodopa - pharmacology Long-Term Potentiation - drug effects l‐dopa Male Mesolimbic system Movement disorders Neostriatum Nucleus accumbens Nucleus Accumbens - drug effects Nucleus Accumbens - physiopathology Oxidopamine Parkinson's disease Parkinsonian Disorders - chemically induced Parkinsonian Disorders - physiopathology plasticity Potentiation Rats Rats, Wistar Rodents Spiny neurons Synaptic plasticity Weight Gain - drug effects impulse control disorders l-dopa plasticity nucleus accumbens
ISSN:	0885-3185, 1531-8257, 1531-8257
Online Access:	Get full text
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