Gene Expression Microarray Data Analysis for Toxicology Profiling

: When dealing with thousands of genes, all potentially interesting, it is desirable to rank the genes according to their degree of participation in a physiological process. Therefore, genes with the highest Shannon entropy and ERL can be selected as the best toxicity target candidates, permitting p...

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Vydané v:	Annals of the New York Academy of Sciences Ročník 919; číslo 1; s. 52 - 67
Hlavní autori:	CUNNINGHAM, M. J., LIANG, S., FURMAN, S., SEILHAMER, J. J., SOMOGYI, R.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Oxford, UK Blackwell Publishing Ltd 01.09.2000
Predmet:	Acetaminophen - pharmacology Animals Benzo(a)pyrene - pharmacology Clofibrate - pharmacology Drug-Related Side Effects and Adverse Reactions - genetics Entropy Gene Expression - drug effects Gene Expression Profiling Liver - drug effects Liver - metabolism Liver - pathology Male Oligonucleotide Array Sequence Analysis Organ Size - drug effects Rats Rats, Sprague-Dawley RNA, Messenger - analysis RNA, Messenger - genetics Toxicity Tests - methods
ISSN:	0077-8923, 1749-6632
On-line prístup:	Získať plný text
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