Gene Expression Microarray Data Analysis for Toxicology Profiling

: When dealing with thousands of genes, all potentially interesting, it is desirable to rank the genes according to their degree of participation in a physiological process. Therefore, genes with the highest Shannon entropy and ERL can be selected as the best toxicity target candidates, permitting p...

Full description

Saved in:

Bibliographic Details
Published in:	Annals of the New York Academy of Sciences Vol. 919; no. 1; pp. 52 - 67
Main Authors:	CUNNINGHAM, M. J., LIANG, S., FURMAN, S., SEILHAMER, J. J., SOMOGYI, R.
Format:	Journal Article
Language:	English
Published:	Oxford, UK Blackwell Publishing Ltd 01.09.2000
Subjects:	Acetaminophen - pharmacology Animals Benzo(a)pyrene - pharmacology Clofibrate - pharmacology Drug-Related Side Effects and Adverse Reactions - genetics Entropy Gene Expression - drug effects Gene Expression Profiling Liver - drug effects Liver - metabolism Liver - pathology Male Oligonucleotide Array Sequence Analysis Organ Size - drug effects Rats Rats, Sprague-Dawley RNA, Messenger - analysis RNA, Messenger - genetics Toxicity Tests - methods
ISSN:	0077-8923, 1749-6632
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!