Ameliorative Effect of Glycyrrhizic Acid on Diosbulbin B-Induced Liver Injury and Its Mechanism

This study aimed to clarify the protective effect of Glycyrrhizic acid (GL) against Diosbulbin B (DB) - induced liver injury in mice and investigate its mechanisms of action. A liver injury DB was established in mice through the oral administration of DB for 15 days. At the same time, GL was adminis...

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Veröffentlicht in:	The American journal of Chinese medicine (1979) Jg. 53; H. 1; S. 309
Hauptverfasser:	Wang, Xin, Shi, Lei-Lei, Zhang, Yu-Han, Zhu, Hong-Zhe, Cao, Shan-Shan, Shi, Yong, Shangguan, Hui-Zi, Liu, Ji-Ping, Xie, Yun-Dong
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Singapore 2025
Schlagworte:	Animals ATP-Binding Cassette Transporters - metabolism Bile Acids and Salts - metabolism Chemical and Drug Induced Liver Injury - drug therapy Chemical and Drug Induced Liver Injury - etiology Chemical and Drug Induced Liver Injury - metabolism Disease Models, Animal Gastrointestinal Microbiome - drug effects Glycyrrhizic Acid - administration & dosage Glycyrrhizic Acid - pharmacology Glycyrrhizic Acid - therapeutic use Heterocyclic Compounds, 4 or More Rings - adverse effects Liver - drug effects Liver - metabolism Liver - pathology Male Mice Oxidative Stress - drug effects Diosbulbin B Bile Acid Glycyrrhizic Acid Hepatotoxicity Intestinal Flora
ISSN:	1793-6853, 1793-6853
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