Transcriptional state and function of CD8 + memory T cells is linked to past proliferation

A new genetic ‘recorder’ of long-term cell proliferation revealed substantial heterogeneity in the division history of central memory CD8+ T cells. Importantly, the extent of past proliferation was related to distinct transcriptional features and re-expansion potential, highlighting an unappreciated...

Full description

Bibliographic Details

Published in:	Nature immunology Vol. 23; no. 5; pp. 658 - 659
Format:	Journal Article
Language:	English
Published:	United States Nature Publishing Group 01.05.2022
Subjects:	CD8 antigen Cell cycle Cell growth Cell proliferation Division of labor Genetic engineering Heterogeneity Immunological memory Immunology Infections Lymphocytes Lymphocytes T Memory cells Population Stem cells
ISSN:	1529-2908, 1529-2916, 1529-2916
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!