Pharmacokinetics, Safety, and Dosing of Novel Pediatric Levofloxacin Dispersible Tablets in Children with Multidrug-Resistant Tuberculosis Exposure

This study characterized the pharmacokinetics of novel 100-mg levofloxacin dispersible tablets in 24 children aged <5 years who had household multidrug-resistant tuberculosus (MDR-TB) exposure. The current data were pooled with previously published data from children ( = 109) with MDR-TB receivi...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy Jg. 63; H. 4
Hauptverfasser:	Garcia-Prats, Anthony J, Purchase, Susan E, Osman, Muhammad, Draper, Heather R, Schaaf, H Simon, Wiesner, Lubbe, Denti, Paolo, Hesseling, Anneke C
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.04.2019
Schlagworte:	Antitubercular Agents - administration & dosage Antitubercular Agents - adverse effects Antitubercular Agents - pharmacokinetics Biological Availability Child, Preschool Female Humans Infant Levofloxacin - administration & dosage Levofloxacin - adverse effects Levofloxacin - pharmacokinetics Male Placebos Tablets Tuberculosis, Multidrug-Resistant - drug therapy Tuberculosis, Multidrug-Resistant - prevention & control bioavailability children levofloxacin formulation pharmacokinetics multidrug-resistant tuberculosis dispersible tablets
ISSN:	1098-6596, 1098-6596
Online-Zugang:	Weitere Angaben
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