Glycan-Modified Melanoma-Derived Apoptotic Extracellular Vesicles as Antigen Source for Anti-Tumor Vaccination

Tumors that lack T cell infiltration are less likely to respond to immune checkpoint inhibition and could benefit from cancer vaccination for the initiation of anti-tumor T cell responses. An attractive vaccine strategy is in vivo targeting of dendritic cells (DCs), key initiators of antigen-specifi...

Full description

Bibliographic Details

Published in:	Cancers Vol. 11; no. 9
Main Authors:	Horrevorts, Sophie K, Stolk, Dorian A, Ven, Rieneke van de, Hulst, Myrthe, Hof, Bert van Het, Duinkerken, Sanne, Heineke, Marieke H, Ma, Wenbin, Dusoswa, Sophie A, Nieuwland, Rienk, Garcia-Vallejo, Juan J, Loosdrecht, Arjan A van de, de Gruijl, Tanja D, Vliet, Sandra J van, van Kooyk, Yvette
Format:	Journal Article
Language:	English
Published:	Switzerland 01.09.2019
Subjects:	T cell priming cancer vaccine glycan modification dendritic cell apoptotic extracellular vesicles C-type lectin
ISSN:	2072-6694, 2072-6694
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!