T cell memory. Skin-resident memory CD8⁺ T cells trigger a state of tissue-wide pathogen alert

After an infection, pathogen-specific tissue-resident memory T cells (T(RM) cells) persist in nonlymphoid tissues to provide rapid control upon reinfection, and vaccination strategies that create T(RM) cell pools at sites of pathogen entry are therefore attractive. However, it is not well understood...

Full description

Bibliographic Details

Published in:	Science (American Association for the Advancement of Science) Vol. 346; no. 6205; p. 101
Main Authors:	Ariotti, Silvia, Hogenbirk, Marc A, Dijkgraaf, Feline E, Visser, Lindy L, Hoekstra, Mirjam E, Song, Ji-Ying, Jacobs, Heinz, Haanen, John B, Schumacher, Ton N
Format:	Journal Article
Language:	English
Published:	United States 03.10.2014
Subjects:	Animals CD8-Positive T-Lymphocytes - immunology Female Immunologic Memory - genetics Immunologic Memory - immunology Male Mice Skin - immunology Skin - microbiology Skin - virology Transcriptome
ISSN:	1095-9203, 1095-9203
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!