T cell memory. Skin-resident memory CD8⁺ T cells trigger a state of tissue-wide pathogen alert

After an infection, pathogen-specific tissue-resident memory T cells (T(RM) cells) persist in nonlymphoid tissues to provide rapid control upon reinfection, and vaccination strategies that create T(RM) cell pools at sites of pathogen entry are therefore attractive. However, it is not well understood...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) Jg. 346; H. 6205; S. 101
Hauptverfasser:	Ariotti, Silvia, Hogenbirk, Marc A, Dijkgraaf, Feline E, Visser, Lindy L, Hoekstra, Mirjam E, Song, Ji-Ying, Jacobs, Heinz, Haanen, John B, Schumacher, Ton N
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 03.10.2014
Schlagworte:	Animals CD8-Positive T-Lymphocytes - immunology Female Immunologic Memory - genetics Immunologic Memory - immunology Male Mice Skin - immunology Skin - microbiology Skin - virology Transcriptome
ISSN:	1095-9203, 1095-9203
Online-Zugang:	Weitere Angaben
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