Hemophagocytic syndrome secondary to cavitary pulmonary tuberculosis
Hemophagocytic syndrome is due to the activation and nonmalignant proliferation of macrophages and T lymphocytes. The purpose of this report is to describe a 25-year-old man who presented with fever, coughing, and weight loss over the past month. Laboratory findings demonstrated pancytopenia, hyperf...
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| Veröffentlicht in: | Médecine et santé tropicales (Montrouge, France) Jg. 22; H. 1; S. 99 |
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| Hauptverfasser: | , , , , , |
| Format: | Journal Article |
| Sprache: | Französisch |
| Veröffentlicht: |
France
01.01.2012
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| Schlagworte: | |
| ISSN: | 2261-2211, 2261-2211 |
| Online-Zugang: | Weitere Angaben |
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| Zusammenfassung: | Hemophagocytic syndrome is due to the activation and nonmalignant proliferation of macrophages and T lymphocytes. The purpose of this report is to describe a 25-year-old man who presented with fever, coughing, and weight loss over the past month. Laboratory findings demonstrated pancytopenia, hyperferritinemia, and cytolysis. The myelogram showed a hemophagocytic syndrome, and tuberculosis bacilli were found in the sputum. Chest radiography and thoracic computed tomography depicted a cavitary lesion suggestive of pulmonary tuberculosis. Treatment of tuberculosis alone, without an immunosuppressant agent, was effective and led to improvement. In a country where tuberculosis is highly endemic, hemophagocytic syndrome should be considered in the differential diagnosis of patients with active tuberculosis complicated by pancytopenia. |
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| Bibliographie: | ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Correspondence-5 ObjectType-Article-4 ObjectType-Report-1 |
| ISSN: | 2261-2211 2261-2211 |
| DOI: | 10.1684/mst.2012.0020 |