Antigen-presenting capacity of rheumatoid synovial fibroblasts

In normal, healthy joints, synovial fibroblasts do not express major histocompatibility complex (MHC) class II molecules. However, in inflamed joints of rheumatoid arthritis (RA) patients, synovial fibroblasts show an abundant expression of MHC class II. Does this increase in expression have functio...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Immunology Jg. 82; H. 2; S. 268
Hauptverfasser:	Boots, A M, Wimmers-Bertens, A J, Rijnders, A W
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England 01.06.1994
Schlagworte:	Antigen-Presenting Cells - immunology Antigens, Bacterial - immunology Antigens, Surface - analysis Arthritis, Rheumatoid - immunology Cell Line Cells, Cultured Dose-Response Relationship, Immunologic Fibroblasts - immunology HLA-DR Antigens - analysis Humans Interferon-gamma - immunology Recombinant Proteins Synovial Membrane - immunology Tetanus Toxoid - immunology
ISSN:	0019-2805
Online-Zugang:	Weitere Angaben
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