Cuproptosis: Cellular and molecular mechanisms underlying copper-induced cell death

Tsvetkov et al. (2022) discovered a new form of cell death triggered by targeted accumulation of Cu in mitochondria that drives lipoylated TCA cycle enzyme aggregation via direct Cu binding.Tsvetkov et al. (2022) discovered a new form of cell death triggered by targeted accumulation of Cu in mitocho...

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Vydáno v:Molecular cell Ročník 82; číslo 10; s. 1786
Hlavní autoři: Cobine, Paul A, Brady, Donita C
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States 19.05.2022
Témata:
Apoptosis
Cell Death
Copper - metabolism
Lipoylation
Mitochondria - metabolism
ISSN:1097-4164, 1097-4164
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Shrnutí:Tsvetkov et al. (2022) discovered a new form of cell death triggered by targeted accumulation of Cu in mitochondria that drives lipoylated TCA cycle enzyme aggregation via direct Cu binding.Tsvetkov et al. (2022) discovered a new form of cell death triggered by targeted accumulation of Cu in mitochondria that drives lipoylated TCA cycle enzyme aggregation via direct Cu binding.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:1097-4164
1097-4164
DOI:10.1016/j.molcel.2022.05.001