Generation of Induced Pluripotent Stem Cell-Like Lines from Human Pancreatic Ductal Adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis, mainly because the tumors are detected too late for effective treatment or for developing suitable therapeutics. Reprogramming cancer cells to pluripotency by induced pluripotent stem cell (iPSC) technology, which can be then programmed...

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Bibliographic Details
Published in:	Methods in molecular biology (Clifton, N.J.) Vol. 1882; p. 33
Main Authors:	Kim, Jungsun, Zaret, Kenneth S
Format:	Journal Article
Language:	English
Published:	United States 2019
Subjects:	Animals Carcinoma, Pancreatic Ductal - pathology Carcinoma, Pancreatic Ductal - therapy Cell Culture Techniques - instrumentation Cell Culture Techniques - methods Cell Differentiation - genetics Cell Line, Tumor Cellular Reprogramming Techniques - methods Fibroblasts Genetic Vectors - genetics HEK293 Cells Humans Induced Pluripotent Stem Cells - pathology Lentivirus - genetics Mice Pancreatic Neoplasms - pathology Pancreatic Neoplasms - therapy Transcription Factors - genetics Transduction, Genetic - instrumentation Transduction, Genetic - methods Xenograft Model Antitumor Assays - methods Induced pluripotent stem cell Pancreatic ductal adenocarcinoma Pancreatic intraepithelial neoplasia
ISSN:	1940-6029, 1940-6029
Online Access:	Get more information
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