Outlier Analysis and Top Scoring Pairfor Integrated Data Analysisand Biomarker Discovery

Pathway deregulation has been identified as a key driver of carcinogenesis, with proteins in signaling pathways serving as primary targets for drug development. Deregulation can be driven by a number of molecular events, including gene mutation, epigenetic changes in gene promoters, overexpression,...

Full description

Bibliographic Details

Published in:	IEEE/ACM transactions on computational biology and bioinformatics Vol. 11; no. 3; pp. 520 - 532
Main Authors:	Ochs, Michael F, Farrar, Jason E, Considine, Michael, Wei, Yingying, Meshinchi, Soheil, Arceci, Robert J
Format:	Journal Article
Language:	English
Published:	New York The Institute of Electrical and Electronics Engineers, Inc. (IEEE) 01.05.2014
Subjects:	Algorithms Biomarkers Carcinogens Deregulation Drugs Genes Medical treatment Pathways Pediatrics Tumors
ISSN:	1545-5963, 1557-9964
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!