Antitumor activity of lycorine in renal cell carcinoma ACHN cell line and its mechanism

To investigate the antitumor effect of lycorine on renal cell carcinoma ACHN cells and explore the possible mechanism. We used flow cytometry to examine the effect of lycorine on ACHN cell cycle and apoptosis. The cell proliferation, migration and invasion were assessed with MTS assay, wound healing...

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Bibliographic Details

Published in:	Nan fang yi ke da xue xue bao = Journal of Southern Medical University Vol. 36; no. 6; p. 857
Main Authors:	Huang, Yi-Qiang, Zhang, Yi-Ming, Jin, Zhong, Li, Xie-Zhao, Wang, Chong-Shan, Xu, Kai, Huang, Peng, Liu, Chun-Xiao
Format:	Journal Article
Language:	Chinese
Published:	China 01.06.2016
Subjects:	Amaryllidaceae Alkaloids - pharmacology Antineoplastic Agents, Phytogenic - pharmacology Apoptosis bcl-2-Associated X Protein - metabolism Carcinoma, Renal Cell - pathology Caspase 3 - metabolism Cell Cycle Checkpoints Cell Line, Tumor - drug effects Cell Proliferation Cyclin D1 - metabolism Cyclin-Dependent Kinase 4 - metabolism Humans Inhibitor of Apoptosis Proteins - metabolism Phenanthridines - pharmacology Proto-Oncogene Proteins c-bcl-2 - metabolism
ISSN:	1673-4254
Online Access:	Get more information
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