Multiorgan and Renal Tropism of SARS-CoV-2

In this autopsy series, the authors found that SARS-CoV-2 has an organotropism beyond the respiratory tract, including the kidneys, heart, liver, and brain. They speculate that organotropism influences the course of Covid-19 disease and, possibly, aggravates preexisting conditions.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:The New England journal of medicine Jg. 383; H. 6; S. 590 - 592
Hauptverfasser: Puelles, Victor G, Lütgehetmann, Marc, Lindenmeyer, Maja T, Sperhake, Jan P, Wong, Milagros N, Allweiss, Lena, Chilla, Silvia, Heinemann, Axel, Wanner, Nicola, Liu, Shuya, Braun, Fabian, Lu, Shun, Pfefferle, Susanne, Schröder, Ann S, Edler, Carolin, Gross, Oliver, Glatzel, Markus, Wichmann, Dominic, Wiech, Thorsten, Kluge, Stefan, Pueschel, Klaus, Aepfelbacher, Martin, Huber, Tobias B
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States Massachusetts Medical Society 06.08.2020
Schlagworte:
Aged
Aged, 80 and over
Autopsy
Betacoronavirus - isolation & purification
Betacoronavirus - physiology
Brain - virology
Brain research
Coronavirus Infections
Coronaviruses
Correspondence
COVID-19
Female
Heart - virology
Humans
Kidney - virology
Kidneys
Liver - virology
Lung - virology
Male
Middle Aged
Organotropism
Pandemics
Pharynx - virology
Pneumonia, Viral
Respiratory tract
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
Tropism
Viral Load
Viral Tropism
ISSN:0028-4793, 1533-4406, 1533-4406
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:In this autopsy series, the authors found that SARS-CoV-2 has an organotropism beyond the respiratory tract, including the kidneys, heart, liver, and brain. They speculate that organotropism influences the course of Covid-19 disease and, possibly, aggravates preexisting conditions.
Bibliographie:SourceType-Scholarly Journals-1
ObjectType-Correspondence-1
content type line 14
ObjectType-Article-2
content type line 23
Drs. Puelles, Lütgehetmann, Lindenmeyer, and Sperhake contributed equally to this letter.
ISSN:0028-4793
1533-4406
1533-4406
DOI:10.1056/NEJMc2011400