Multiorgan and Renal Tropism of SARS-CoV-2

In this autopsy series, the authors found that SARS-CoV-2 has an organotropism beyond the respiratory tract, including the kidneys, heart, liver, and brain. They speculate that organotropism influences the course of Covid-19 disease and, possibly, aggravates preexisting conditions.

Uloženo v:
Podrobná bibliografie
Vydáno v:The New England journal of medicine Ročník 383; číslo 6; s. 590 - 592
Hlavní autoři: Puelles, Victor G, Lütgehetmann, Marc, Lindenmeyer, Maja T, Sperhake, Jan P, Wong, Milagros N, Allweiss, Lena, Chilla, Silvia, Heinemann, Axel, Wanner, Nicola, Liu, Shuya, Braun, Fabian, Lu, Shun, Pfefferle, Susanne, Schröder, Ann S, Edler, Carolin, Gross, Oliver, Glatzel, Markus, Wichmann, Dominic, Wiech, Thorsten, Kluge, Stefan, Pueschel, Klaus, Aepfelbacher, Martin, Huber, Tobias B
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States Massachusetts Medical Society 06.08.2020
Témata:
Aged
Aged, 80 and over
Autopsy
Betacoronavirus - isolation & purification
Betacoronavirus - physiology
Brain - virology
Brain research
Coronavirus Infections
Coronaviruses
Correspondence
COVID-19
Female
Heart - virology
Humans
Kidney - virology
Kidneys
Liver - virology
Lung - virology
Male
Middle Aged
Organotropism
Pandemics
Pharynx - virology
Pneumonia, Viral
Respiratory tract
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
Tropism
Viral Load
Viral Tropism
ISSN:0028-4793, 1533-4406, 1533-4406
On-line přístup:Získat plný text
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
Popis
Shrnutí:In this autopsy series, the authors found that SARS-CoV-2 has an organotropism beyond the respiratory tract, including the kidneys, heart, liver, and brain. They speculate that organotropism influences the course of Covid-19 disease and, possibly, aggravates preexisting conditions.
Bibliografie:SourceType-Scholarly Journals-1
ObjectType-Correspondence-1
content type line 14
ObjectType-Article-2
content type line 23
Drs. Puelles, Lütgehetmann, Lindenmeyer, and Sperhake contributed equally to this letter.
ISSN:0028-4793
1533-4406
1533-4406
DOI:10.1056/NEJMc2011400