Inflammatory and neurodegenerative serum protein biomarkers increase sensitivity to detect disease activity in multiple sclerosis

Serum proteomic analysis of deeply-phenotyped samples, biological pathway modeling and network analysis were performed to elucidate the inflammatory and neurodegenerative processes of multiple sclerosis (MS) and identify sensitive biomarkers of MS disease activity (DA). Over 1100 serum proteins were...

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Veröffentlicht in:medRxiv : the preprint server for health sciences
Hauptverfasser: Chitnis, Tanuja, Qureshi, Ferhan, Gehman, Victor M, Becich, Michael, Bove, Riley, Cree, Bruce A C, Gomez, Refujia, Hauser, Stephen L, Henry, Roland G, Katrib, Amal, Lokhande, Hrishikesh, Paul, Anu, Caillier, Stacy J, Santaniello, Adam, Sattarnezhad, Neda, Saxena, Shrishti, Weiner, Howard, Yano, Hajime, Baranzini, Sergio E
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States 03.07.2023
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