Mixture modeling of next generation sequencing data and its applications to genotyping and estimating genotype frequencies
Estimating the probability that an individual has a base pair nucleodite different from the reference nucleotide is important in next generation sequencing (NGS) research. I present a method for modeling the frequency of single nucleotide polymorphism variants in the exome capturing sequence data of...
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| Médium: | Dissertation |
| Jazyk: | English |
| Vydavateľské údaje: |
ProQuest Dissertations & Theses
01.01.2013
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| Predmet: | |
| ISBN: | 9781303807114, 1303807114 |
| On-line prístup: | Získať plný text |
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