Tests for detection of rare variants and gene-environment interaction in cohort and twin family studies

Complex diseases are caused by a combination of environmental and genetic factors. While we have estimated that genetic factors explain a large proportion of variance in many of these diseases, current strategies using only the genotyped common variants (CVs) have failed to explain all of this herit...

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Bibliographic Details
Main Author:	Coombes, Brandon J
Format:	Dissertation
Language:	English
Published:	ProQuest Dissertations & Theses 01.01.2016
Subjects:	Biostatistics Genetics Statistics
ISBN:	1369354908, 9781369354904
Online Access:	Get full text
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