I Think the Work Has Principal Application to Immunology
By the late summer of 1949, Jerne had sufficient experiments behind him to be able to choose between the univalence theory and the multivalence theory. The theoretical curves derived from the univalence theory did not match the experimental data well, whereas the curves that had been derived from th...
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| Veröffentlicht in: | Science as Autobiography S. 124 |
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| 1. Verfasser: | |
| Format: | Buchkapitel |
| Sprache: | Englisch |
| Veröffentlicht: |
Yale University Press
11.03.2003
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| Schlagworte: | |
| ISBN: | 0300094418, 9780300094411 |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | By the late summer of 1949, Jerne had sufficient experiments behind him to be able to choose between the univalence theory and the multivalence theory. The theoretical curves derived from the univalence theory did not match the experimental data well, whereas the curves that had been derived from the multivalence theory did; hence the multivalence model permitted a “reasonable explanation of the experimental data.” He could show that high values of the reaction constant correspond to the steep neutralization curves obtained on titration of high-avidity sera (for example, standard serum), and low values to the more horizontal neutralization curves obtained |
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| ISBN: | 0300094418 9780300094411 |
| DOI: | 10.12987/yale/9780300094411.003.0011 |