Aberrant DNA methylation impacts gene expression and prognosis in breast cancer subtypes

DNA methylation has a substantial impact on gene expression, affecting the prognosis of breast cancer (BC) patients dependent on molecular subtypes. In this study, we investigated the prognostic relevance of the expression of genes reported as aberrantly methylated, and the link between gene express...

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Veröffentlicht in:	International journal of cancer Jg. 138; H. 1; S. 87 - 97
Hauptverfasser:	Győrffy, Balázs, Bottai, Giulia, Fleischer, Thomas, Munkácsy, Gyöngyi, Budczies, Jan, Paladini, Laura, Børresen‐Dale, Anne‐Lise, Kristensen, Vessela N., Santarpia, Libero
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Wiley Subscription Services, Inc 01.01.2016
Schlagworte:	Biomarkers Biomarkers, Tumor - genetics Breast cancer breast cancer subtypes Breast Neoplasms - diagnosis Breast Neoplasms - genetics Breast Neoplasms - mortality Cancer Deoxyribonucleic acid DNA DNA Methylation DNA methylation biomarkers Epigenesis, Genetic Female Gene expression Gene Expression Profiling Gene Expression Regulation, Neoplastic Humans immune genes Kaplan-Meier Estimate Medical prognosis Medical research Prognosis Transcriptome immune genes breast cancer subtypes DNA methylation biomarkers prognosis gene expression
ISSN:	0020-7136, 1097-0215, 1097-0215
Online-Zugang:	Volltext
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