Effect of rinsing with ethanol-containing mouthrinses on the production of salivary acetaldehyde

Moazzez R, Thompson H, Palmer RM, Wilson RF, Proctor GB, Wade WG. Effect of rinsing with ethanol‐containing mouthrinses on the production of salivary acetaldehyde. 
 Eur J Oral Sci 2011; 119: 441–446. © 2011 Eur J Oral Sci It has been suggested that the use of alcohol‐containing mouthrinses could le...

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Vydáno v:European journal of oral sciences Ročník 119; číslo 6; s. 441 - 446
Hlavní autoři: Moazzez, Rebecca, Thompson, Hayley, Palmer, Richard M., Wilson, Ron F., Proctor, Gordon B., Wade, William G.
Médium: Journal Article
Jazyk:angličtina
Vydáno: Oxford, UK Blackwell Publishing Ltd 01.12.2011
Témata:
acetaldehyde
Acetaldehyde - metabolism
Adult
Anti-Infective Agents, Local - administration & dosage
Anti-Infective Agents, Local - metabolism
bacteria
Cross-Over Studies
Dental Plaque - metabolism
Dental Plaque - microbiology
Dental Plaque - prevention & control
Double-Blind Method
ethanol
Ethanol - administration & dosage
Ethanol - metabolism
Female
Humans
Male
Microbial Consortia
Mouth - drug effects
Mouth - metabolism
Mouth - microbiology
mouthrinse
Mouthwashes - metabolism
Saliva - drug effects
Saliva - metabolism
Yeasts
ISSN:0909-8836, 1600-0722, 1600-0722
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Shrnutí:Moazzez R, Thompson H, Palmer RM, Wilson RF, Proctor GB, Wade WG. Effect of rinsing with ethanol‐containing mouthrinses on the production of salivary acetaldehyde. 
 Eur J Oral Sci 2011; 119: 441–446. © 2011 Eur J Oral Sci It has been suggested that the use of alcohol‐containing mouthrinses could lead to the presence of acetaldehyde in saliva. In this cross‐over study, salivary acetaldehyde levels and microbial profiles were determined before and after rinsing with ethanol‐containing mouthrinses with essential oils (EO) and cetyl pyridinium chloride (CPC) as the active ingredients, and with 21.6% ethanol and water controls. After rinsing with all ethanol‐containing rinses, acetaldehyde was detected in saliva after 30 s but declined to low levels after 5 min. The highest peak levels were seen with the ethanol control (median = 82.9 μM at 2 min) and were significantly higher than those seen at the same time after rinsing with the EO rinse (43.1 μM). There was no correlation between microbial counts or plaque scores and acetaldehyde levels, although dividing the subjects on the basis of a peak acetaldehyde salivary concentration of > 90.8 μM after the ethanol rinse revealed that the high responders were highly significantly more likely to harbour salivary yeasts than were the low responders. Rinsing with ethanol‐containing mouthrinses causes a rapid, but transient, increase in salivary acetaldehyde levels.
Bibliografie:ArticleID:EOS886
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istex:22BED54246776D04470A367659EA56A442FCE331
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0909-8836
1600-0722
1600-0722
DOI:10.1111/j.1600-0722.2011.00886.x