Evaluating Grasp-based cloud dimensioning for comparative genomics: A practical approach

Cloud computing establishes a new computing model where a wide range of computing resources are provided to several types of users. Especially for bioinformatics experiments modeled as scientific workflows, clouds provide several types of resources as virtual machines (VM), storage, databases and co...

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Bibliographic Details
Published in:Proceedings / IEEE International Conference on Cluster Computing pp. 371 - 379
Main Authors: Coutinho, Rafaelli, Drummond, Lucia, Frota, Yuri, de Oliveira, Daniel, Ocana, Kary
Format: Conference Proceeding
Language:English
Published: IEEE 01.09.2014
Subjects:
Bioinformatics
Bioinformatics Workflows
Cloud Computing
Computational modeling
Drugs
Estimation
Genomics
Hidden Markov models
Phylogeny
Virtual Machine Allocation
ISSN:1552-5244
Online Access:Get full text
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Summary:Cloud computing establishes a new computing model where a wide range of computing resources are provided to several types of users. Especially for bioinformatics experiments modeled as scientific workflows, clouds provide several types of resources as virtual machines (VM), storage, databases and computing power that can be combined for empowering the scientific workflow execution. These workflows usually require high performance environments and parallelism techniques since their activities are data and computing intensive and can execute for a long time. There are then some Scientific Workflow Management Systems (SWfMS) that already manage the parallel execution of scientific workflows in clouds. Most of them instantiate a virtual cluster for the execution. However, they rely on the user to estimate the amount of VMs to be instantiated to create this virtual cluster. Estimating the amount of VMs to instantiate is then a crucial task to avoid negative impacts on the workflow performance with under or over estimations. This dimensioning also is not a trivial task in clouds due to the large number of VM types to choose in a cloud provider. Previously proposed approach named GraspCC already provides a near optimal estimation of the amount of VM for general applications, not scientific workflows. In this paper, we coupled the GraspCC to SciCumulus (Cloud-based Parallel Engine for Scientific Workflows) engine to estimate the necessary amount of VMs for bioinformatics workflows. We have evaluated GraspCC by comparing the estimative with real executions of a set of large-scale comparative genomics workflows. It showed the suitability of GraspCC to estimate the amount of VMs in real bioinformatics cloud workflows.
ISSN:1552-5244
DOI:10.1109/CLUSTER.2014.6968789